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VAX1 and POLR3C
Data Source:
BioGRID
(two hybrid)
VAX1
POLR3C
Description
ventral anterior homeobox 1
RNA polymerase III subunit C
Image
No pdb structure
GO Annotations
Cellular Component
Chromatin
Nucleus
Nucleoplasm
RNA Polymerase III Complex
Cytosol
Molecular Function
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
RNA Polymerase II Intronic Transcription Regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific
Chromatin DNA Binding
Sequence-specific Double-stranded DNA Binding
Single-stranded DNA Binding
DNA-directed 5'-3' RNA Polymerase Activity
Protein Binding
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Neuron Migration
Regulation Of Transcription By RNA Polymerase II
Negative Regulation Of Neuroblast Proliferation
Axon Guidance
Central Nervous System Development
Brain Development
Neuron Differentiation
Skeletal Muscle Cell Differentiation
Camera-type Eye Development
Roof Of Mouth Development
Transcription, DNA-templated
Regulation Of Transcription By RNA Polymerase III
Positive Regulation Of Type I Interferon Production
Positive Regulation Of Interferon-beta Production
Innate Immune Response
Positive Regulation Of Innate Immune Response
Defense Response To Virus
Pathways
Cytosolic sensors of pathogen-associated DNA
RNA Polymerase III Chain Elongation
RNA Polymerase III Transcription Termination
RNA Polymerase III Abortive And Retractive Initiation
RNA Polymerase III Transcription Initiation From Type 1 Promoter
RNA Polymerase III Transcription Initiation From Type 1 Promoter
RNA Polymerase III Transcription Initiation From Type 2 Promoter
RNA Polymerase III Transcription Initiation From Type 2 Promoter
RNA Polymerase III Transcription Initiation From Type 3 Promoter
RNA Polymerase III Transcription Initiation From Type 3 Promoter
Drugs
Diseases
GWAS
Body mass index (
26426971
)
Brain morphology (MOSTest) (
32665545
)
Cleft lip with or without cleft palate (
28054174
)
Nonsyndromic cleft lip (
31609978
)
Nonsyndromic cleft lip with cleft palate (
28232668
)
Nonsyndromic cleft lip with or without cleft palate (
25775280
)
Orofacial clefts (
20023658
28054174
)
Interacting Genes
14 interacting genes:
DVL3
EAF1
ESRRG
HECW1
HMBOX1
MLLT3
PICK1
POLR3C
PSMB1
RCOR3
RPRD1B
SDCBP2
SPANXN2
USP20
39 interacting genes:
ANKRD23
APP
CAMK2B
CEP44
CEP63
COIL
DISC1
ENKD1
GOLGA2
GTF3C4
HAUS1
INCA1
KATNBL1
KIAA0408
KLHL2
KPNA1
KPNA3
KPNA5
KPNA6
KRT75
LZTS1
NCKIPSD
PAX6
PICK1
PNMA5
POLR3G
POLR3GL
POU6F2
PRDM16
RBBP8NL
ROCK1
ROPN1
SP100
TNR
TRAF2
TRIM27
UBXN1
VAX1
VRTN
Entrez ID
11023
10623
HPRD ID
16052
17880
Ensembl ID
ENSG00000148704
ENSG00000186141
Uniprot IDs
Q5SQQ9
Q9BUI4
PDB IDs
2XUB
2XV4
5AFQ
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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