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POLR3C and UBXN1
Data Source:
BioGRID
(two hybrid)
POLR3C
UBXN1
Description
RNA polymerase III subunit C
UBX domain protein 1
Image
No pdb structure
GO Annotations
Cellular Component
Nucleoplasm
RNA Polymerase III Complex
Cytosol
Nucleoplasm
Cytoplasm
Endoplasmic Reticulum
Cytosol
Dendrite
VCP-NPL4-UFD1 AAA ATPase Complex
Neuronal Cell Body
Molecular Function
Single-stranded DNA Binding
DNA-directed 5'-3' RNA Polymerase Activity
Protein Binding
Protein Binding
Polyubiquitin Modification-dependent Protein Binding
Ubiquitin Protein Ligase Binding
K48-linked Polyubiquitin Modification-dependent Protein Binding
Ubiquitin Binding
ATPase Binding
K6-linked Polyubiquitin Modification-dependent Protein Binding
Proteasome Regulatory Particle Binding
Biological Process
Transcription, DNA-templated
Regulation Of Transcription By RNA Polymerase III
Positive Regulation Of Type I Interferon Production
Positive Regulation Of Interferon-beta Production
Innate Immune Response
Positive Regulation Of Innate Immune Response
Defense Response To Virus
Protein Folding
Viral Process
Negative Regulation Of Protein Ubiquitination
Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Negative Regulation Of Protein K48-linked Deubiquitination
Negative Regulation Of ERAD Pathway
Negative Regulation Of Ubiquitin-specific Protease Activity
Pathways
Cytosolic sensors of pathogen-associated DNA
RNA Polymerase III Chain Elongation
RNA Polymerase III Transcription Termination
RNA Polymerase III Abortive And Retractive Initiation
RNA Polymerase III Transcription Initiation From Type 1 Promoter
RNA Polymerase III Transcription Initiation From Type 1 Promoter
RNA Polymerase III Transcription Initiation From Type 2 Promoter
RNA Polymerase III Transcription Initiation From Type 2 Promoter
RNA Polymerase III Transcription Initiation From Type 3 Promoter
RNA Polymerase III Transcription Initiation From Type 3 Promoter
N-glycan trimming in the ER and Calnexin/Calreticulin cycle
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks
Drugs
Diseases
GWAS
Waist-to-hip ratio adjusted for BMI (
26426971
)
Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) (
26426971
)
Interacting Genes
39 interacting genes:
ANKRD23
APP
CAMK2B
CEP44
CEP63
COIL
DISC1
ENKD1
GOLGA2
GTF3C4
HAUS1
INCA1
KATNBL1
KIAA0408
KLHL2
KPNA1
KPNA3
KPNA5
KPNA6
KRT75
LZTS1
NCKIPSD
PAX6
PICK1
PNMA5
POLR3G
POLR3GL
POU6F2
PRDM16
RBBP8NL
ROCK1
ROPN1
SP100
TNR
TRAF2
TRIM27
UBXN1
VAX1
VRTN
19 interacting genes:
ACOT7
ACVR1
BARD1
BMPR1B
BRCA1
FAM189A2
HOMER2
PLA2G4A
PLAA
POLR3C
RAD23A
SMAD1
SMURF1
TGFBR1
TRIM39
UBC
UBE2I
UBQLN1
UBQLN2
Entrez ID
10623
51035
HPRD ID
17880
11266
Ensembl ID
ENSG00000186141
ENSG00000162191
Uniprot IDs
Q9BUI4
A0A024R539
A0A024R598
A0A087WTZ5
Q04323
PDB IDs
2XUB
2XV4
5AFQ
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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