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POLR3C and KPNA1
Data Source:
BioGRID
(two hybrid)
POLR3C
KPNA1
Description
RNA polymerase III subunit C
karyopherin subunit alpha 1
Image
GO Annotations
Cellular Component
Nucleoplasm
RNA Polymerase III Complex
Cytosol
Nucleus
Nuclear Pore
Nucleoplasm
Cytoplasm
Cytosol
Postsynaptic Density
Dendrite
Host Cell
Glutamatergic Synapse
Molecular Function
Single-stranded DNA Binding
DNA-directed 5'-3' RNA Polymerase Activity
Protein Binding
Protein Binding
Nuclear Localization Sequence Binding
Nuclear Import Signal Receptor Activity
Biological Process
Transcription, DNA-templated
Regulation Of Transcription By RNA Polymerase III
Positive Regulation Of Type I Interferon Production
Positive Regulation Of Interferon-beta Production
Innate Immune Response
Positive Regulation Of Innate Immune Response
Defense Response To Virus
Regulation Of DNA Recombination
Apoptotic DNA Fragmentation
NLS-bearing Protein Import Into Nucleus
Skeletal Muscle Satellite Cell Proliferation
Satellite Cell Activation Involved In Skeletal Muscle Regeneration
Modulation By Virus Of Host Cellular Process
Regulation Of Apoptotic Process
Regulation Of Canonical Wnt Signaling Pathway
Intracellular Transport Of Virus
Postsynapse To Nucleus Signaling Pathway
Pathways
Cytosolic sensors of pathogen-associated DNA
RNA Polymerase III Chain Elongation
RNA Polymerase III Transcription Termination
RNA Polymerase III Abortive And Retractive Initiation
RNA Polymerase III Transcription Initiation From Type 1 Promoter
RNA Polymerase III Transcription Initiation From Type 1 Promoter
RNA Polymerase III Transcription Initiation From Type 2 Promoter
RNA Polymerase III Transcription Initiation From Type 2 Promoter
RNA Polymerase III Transcription Initiation From Type 3 Promoter
RNA Polymerase III Transcription Initiation From Type 3 Promoter
ISG15 antiviral mechanism
Apoptosis induced DNA fragmentation
Integration of provirus
Transport of Ribonucleoproteins into the Host Nucleus
NS1 Mediated Effects on Host Pathways
Vpr-mediated nuclear import of PICs
Inhibition of nitric oxide production
Drugs
Diseases
GWAS
Calcium levels (
20705733
)
LDL cholesterol (
30275531
)
LDL cholesterol levels (
28334899
)
Mean corpuscular hemoglobin (
32888494
)
Parkinson's disease or first degree relation to individual with Parkinson's disease (
31701892
)
Interacting Genes
39 interacting genes:
ANKRD23
APP
CAMK2B
CEP44
CEP63
COIL
DISC1
ENKD1
GOLGA2
GTF3C4
HAUS1
INCA1
KATNBL1
KIAA0408
KLHL2
KPNA1
KPNA3
KPNA5
KPNA6
KRT75
LZTS1
NCKIPSD
PAX6
PICK1
PNMA5
POLR3G
POLR3GL
POU6F2
PRDM16
RBBP8NL
ROCK1
ROPN1
SP100
TNR
TRAF2
TRIM27
UBXN1
VAX1
VRTN
45 interacting genes:
ANP32A
ANP32B
ARNT
BCAR3
CDKN1B
CLK4
CRADD
CSE1L
ELAVL1
EPAS1
FOSL1
GOPC
GTF2IRD1
H2BC21
H3-4
HDAC6
HIF1A
IL1RAP
KPNB1
LEF1
LINC01554
LMNB1
LMO4
MACROD1
MDM2
NMNAT1
NOSIP
NUP50
NUP54
NUP62
ORC4
PAX5
PKM
POLR3C
RAG1
RANBP2
RUNX1T1
SENP2
SKP2
SRP19
STAT1
STAT3
TAF9
UBR5
USP1
Entrez ID
10623
3836
HPRD ID
17880
02819
Ensembl ID
ENSG00000186141
ENSG00000114030
Uniprot IDs
Q9BUI4
B3KXZ2
P52294
PDB IDs
2XUB
2XV4
5AFQ
2JDQ
3TJ3
4B18
6WX9
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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