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VAX1

Description ventral anterior homeobox 1
Image No pdb structure
GO Annotations Cellular Component
  • Chromatin
  • Nucleus
Molecular Function
  • RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
  • DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
  • RNA Polymerase II Intronic Transcription Regulatory Region Sequence-specific DNA Binding
  • DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific
  • Chromatin DNA Binding
  • Sequence-specific Double-stranded DNA Binding
Biological Process
  • Negative Regulation Of Transcription By RNA Polymerase II
  • Neuron Migration
  • Regulation Of Transcription By RNA Polymerase II
  • Negative Regulation Of Neuroblast Proliferation
  • Axon Guidance
  • Central Nervous System Development
  • Brain Development
  • Neuron Differentiation
  • Skeletal Muscle Cell Differentiation
  • Camera-type Eye Development
  • Roof Of Mouth Development
Pathways
Drugs
Diseases
GWAS
  • Body mass index ( 26426971)
  • Brain morphology (MOSTest) ( 32665545)
  • Cleft lip with or without cleft palate ( 28054174)
  • Nonsyndromic cleft lip ( 31609978)
  • Nonsyndromic cleft lip with cleft palate ( 28232668)
  • Nonsyndromic cleft lip with or without cleft palate ( 25775280)
  • Orofacial clefts ( 20023658 28054174)
Interacting Genes 14 interacting genes: DVL3 EAF1 ESRRG HECW1 HMBOX1 MLLT3 PICK1 POLR3C PSMB1 RCOR3 RPRD1B SDCBP2 SPANXN2 USP20
Entrez ID 11023
HPRD ID 16052
Ensembl ID ENSG00000148704
Uniprot IDs Q5SQQ9
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?

© Madhavi K. Ganapathiraju 2012-2025