FARP1 and PIH1D1

Data Source:
BioGRID (two hybrid)

		FARP1	PIH1D1
Description		FERM, ARH/RhoGEF and pleckstrin domain protein 1	PIH1 domain containing 1
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GO Annotations	Cellular Component	Cytosol Cytoskeleton Filopodium Dendrite Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane Dendritic Spine	Nucleus Nucleolus Cytoplasm Pre-snoRNP Complex R2TP Complex Ribonucleoprotein Complex
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Protein Binding Cytoskeletal Protein Binding	RNA Polymerase I Core Promoter Sequence-specific DNA Binding RNA Polymerase I Cis-regulatory Region Sequence-specific DNA Binding Protein Binding Protein Kinase Binding Histone Binding ATPase Binding Phosphoprotein Binding
	Biological Process	Synapse Assembly Negative Regulation Of Phosphatase Activity Dendrite Morphogenesis	Box C/D SnoRNP Assembly RNA Polymerase I Preinitiation Complex Assembly Chromatin Remodeling RRNA Processing Epithelial Cell Differentiation Positive Regulation Of Protein-containing Complex Assembly SnoRNA Localization Regulation Of Histone H3-K4 Methylation Establishment Of Protein Localization To Chromatin Positive Regulation Of Protein Serine/threonine Kinase Activity Positive Regulation Of Histone H4 Acetylation Negative Regulation Of Histone H3-K9 Dimethylation Negative Regulation Of Histone H3-K9 Trimethylation Positive Regulation Of Transcription Of Nucleolar Large RRNA By RNA Polymerase I Positive Regulation Of Glucose Mediated Signaling Pathway Regulation Of TORC2 Signaling Positive Regulation Of TORC1 Signaling Positive Regulation Of Histone H3-K9 Acetylation Negative Regulation Of Histone H4-K16 Acetylation Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Signaling Pathway
Pathways
Drugs
Diseases
GWAS		Alzheimer disease and age of onset ( 26830138) Brain structure ( 20171287) Clozapine-induced agranulocytosis ( 25187353) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Coronary artery disease ( 33020668) Educational attainment ( 25201988) General factor of neuroticism ( 30867560) Household income ( 31844048) Household income (MTAG) ( 31844048) Ischemic stroke (large artery atherosclerosis) ( 29531354) Mood instability ( 31168069) Non-alcoholic fatty liver disease histology (lobular) ( 20708005) Obesity-related traits ( 23251661) Pelvic organ prolapse ( 26545240) Pneumococcal meningitis x streptococcus pneumoniae antigen allele interaction ( 31092817) Response to amphetamines ( 22952603) Social science traits (pleiotropy) (HIPO component 1) ( 30289880) Total ventricular volume (Alzheimer's disease interaction) ( 21116278)
Interacting Genes		1 interacting genes: PIH1D1	20 interacting genes: BYSL CA4 CDCA7L EAF1 FAM90A1 FARP1 GEM LRCH3 MAPK6 MFAP1 MISP PLEKHN1 RBPMS RCOR3 RPAP2 SCNM1 SEPTIN1 SMARCD1 TNS4 TSC22D4
Entrez ID		10160	55011
HPRD ID		16006	07938
Ensembl ID		ENSG00000152767	ENSG00000104872
Uniprot IDs		A0A2X0TVY0 C9JME2 Q9Y4F1	Q9NWS0
PDB IDs		4H6Y	4PSF 4PSI 6GXZ
Enriched GO Terms of Interacting Partners?
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