PIH1D1 and RCOR3

Data Source:
BioGRID (two hybrid)

		PIH1D1	RCOR3
Description		PIH1 domain containing 1	REST corepressor 3
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GO Annotations	Cellular Component	Nucleus Nucleolus Cytoplasm Pre-snoRNP Complex R2TP Complex Ribonucleoprotein Complex	Histone Deacetylase Complex Nucleoplasm Transcription Regulator Complex Cytosol
	Molecular Function	RNA Polymerase I Core Promoter Sequence-specific DNA Binding RNA Polymerase I Cis-regulatory Region Sequence-specific DNA Binding Protein Binding Protein Kinase Binding Histone Binding ATPase Binding Phosphoprotein Binding	Transcription Corepressor Activity Protein Binding
	Biological Process	Box C/D SnoRNP Assembly RNA Polymerase I Preinitiation Complex Assembly Chromatin Remodeling RRNA Processing Epithelial Cell Differentiation Positive Regulation Of Protein-containing Complex Assembly SnoRNA Localization Regulation Of Histone H3-K4 Methylation Establishment Of Protein Localization To Chromatin Positive Regulation Of Protein Serine/threonine Kinase Activity Positive Regulation Of Histone H4 Acetylation Negative Regulation Of Histone H3-K9 Dimethylation Negative Regulation Of Histone H3-K9 Trimethylation Positive Regulation Of Transcription Of Nucleolar Large RRNA By RNA Polymerase I Positive Regulation Of Glucose Mediated Signaling Pathway Regulation Of TORC2 Signaling Positive Regulation Of TORC1 Signaling Positive Regulation Of Histone H3-K9 Acetylation Negative Regulation Of Histone H4-K16 Acetylation Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Signaling Pathway	Regulation Of Transcription By RNA Polymerase II Histone Deacetylation Negative Regulation Of Transcription, DNA-templated
Pathways
Drugs
Diseases
GWAS			Plateletcrit ( 32888494)
Interacting Genes		20 interacting genes: BYSL CA4 CDCA7L EAF1 FAM90A1 FARP1 GEM LRCH3 MAPK6 MFAP1 MISP PLEKHN1 RBPMS RCOR3 RPAP2 SCNM1 SEPTIN1 SMARCD1 TNS4 TSC22D4	74 interacting genes: ABI1 ANKRD11 APP BHLHB9 BORCS6 CBY2 CCDC102B CCDC106 CCHCR1 CDR2 CEP55 CEP63 CEP70 EFHC2 FAM81A FSD2 GKAP1 GLRX3 GOLGA2 GRIPAP1 GSE1 HAUS3 HMBOX1 HOOK2 HSF2BP ICA1L IKZF3 ING5 ISY1-RAB43 KDM1A KRT15 KRT18 KRT19 KRT24 KRT27 KRT31 KRT40 KRT75 LCA5 LHX3 LUZP4 LZTS2 MAGEA6 MCC MESD MID2 MIPOL1 MTUS2 NDUFB7 NECAB2 NINL NRDE2 NUTM1 PHF19 PHF21B PIH1D1 PRDM14 PTTG2 STN1 SUMO2 TFIP11 TRAF1 TRAF2 TRIM27 TRIM42 TRIM54 TSGA10 TULP3 TXLNA USHBP1 VAX1 YWHAQ ZNF383 ZNF688
Entrez ID		55011	55758
HPRD ID		07938	08338
Ensembl ID		ENSG00000104872	ENSG00000117625
Uniprot IDs		Q9NWS0	Q9P2K3
PDB IDs		4PSF 4PSI 6GXZ	4CZZ
Enriched GO Terms of Interacting Partners?
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