PIH1D1 and MFAP1

Data Source:
BioGRID (two hybrid)

		PIH1D1	MFAP1
Description		PIH1 domain containing 1	microfibril associated protein 1
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GO Annotations	Cellular Component	Nucleus Nucleolus Cytoplasm Pre-snoRNP Complex R2TP Complex Ribonucleoprotein Complex	Microfibril Extracellular Region Nucleus Nucleoplasm U2-type Spliceosomal Complex Centrosome U2-type Precatalytic Spliceosome
	Molecular Function	RNA Polymerase I Core Promoter Sequence-specific DNA Binding RNA Polymerase I Cis-regulatory Region Sequence-specific DNA Binding Protein Binding Protein Kinase Binding Histone Binding ATPase Binding Phosphoprotein Binding	RNA Binding Protein Binding
	Biological Process	Box C/D SnoRNP Assembly RNA Polymerase I Preinitiation Complex Assembly Chromatin Remodeling RRNA Processing Epithelial Cell Differentiation Positive Regulation Of Protein-containing Complex Assembly SnoRNA Localization Regulation Of Histone H3-K4 Methylation Establishment Of Protein Localization To Chromatin Positive Regulation Of Protein Serine/threonine Kinase Activity Positive Regulation Of Histone H4 Acetylation Negative Regulation Of Histone H3-K9 Dimethylation Negative Regulation Of Histone H3-K9 Trimethylation Positive Regulation Of Transcription Of Nucleolar Large RRNA By RNA Polymerase I Positive Regulation Of Glucose Mediated Signaling Pathway Regulation Of TORC2 Signaling Positive Regulation Of TORC1 Signaling Positive Regulation Of Histone H3-K9 Acetylation Negative Regulation Of Histone H4-K16 Acetylation Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Signaling Pathway	MRNA Splicing, Via Spliceosome
Pathways			Molecules associated with elastic fibres
Drugs
Diseases
GWAS			Lipoprotein phospholipase A2 activity in cardiovascular disease ( 28753643)
Interacting Genes		20 interacting genes: BYSL CA4 CDCA7L EAF1 FAM90A1 FARP1 GEM LRCH3 MAPK6 MFAP1 MISP PLEKHN1 RBPMS RCOR3 RPAP2 SCNM1 SEPTIN1 SMARCD1 TNS4 TSC22D4	90 interacting genes: ALKBH8 AMOTL2 AP2M1 BEND7 BHLHB9 BICD2 CARD9 CCDC102B CCDC33 CCDC57 CDC14B CDCA7L CEP55 CEP57L1 CEP70 CEP76 COG6 COIL CSNK2A1 DHX38 DHX8 DNTTIP1 FAM9B FRA10AC1 FXR1 FXR2 GAS8 GKAP1 GOLGA2 GOLGA6L9 GRIPAP1 HMBOX1 HOMER3 HOOK2 HSF2BP HSPB1 IK KATNBL1 KIFC3 KLHL2 KRT40 L3MBTL3 LDOC1 LMNA LMNB2 LZTS1 MAD1L1 MCRS1 MID2 MIPOL1 MTUS2 NDC80 NGDN OLIG3 PAX6 PHC2 PIBF1 PIH1D1 PLEKHF2 SART1 SNW1 SSX2IP STAC3 STX11 TADA2A TCP10L TEPSIN TFIP11 THAP1 TLE5 TRAF2 TRIM41 TRIM42 TRIM54 U2AF1 VPS52 YWHAG ZBTB1 ZBTB14 ZBTB8A ZFP1 ZFP41 ZFP64 ZNF398 ZNF41 ZNF558 ZNF620 ZNF71 ZNF76 ZRANB1
Entrez ID		55011	4236
HPRD ID		07938	02569
Ensembl ID		ENSG00000104872	ENSG00000140259
Uniprot IDs		Q9NWS0	P55081
PDB IDs		4PSF 4PSI 6GXZ	5F5S 5O9Z 6AHD
Enriched GO Terms of Interacting Partners?
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