TOMM20 and OTC

Number of citations of the paper that reports this interaction (PubMedID 9756929)
10

Data Source:
BioGRID (pull down)
HPRD (in vitro)

		TOMM20	OTC
Description		translocase of outer mitochondrial membrane 20	ornithine carbamoyltransferase
Image
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Outer Membrane Mitochondrial Outer Membrane Translocase Complex Integral Component Of Mitochondrial Outer Membrane Mitochondria-associated ER Membrane	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Matrix Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding P-P-bond-hydrolysis-driven Protein Transmembrane Transporter Activity Mitochondrion Targeting Sequence Binding Unfolded Protein Binding	Ornithine Carbamoyltransferase Activity Phospholipid Binding Amino Acid Binding Phosphate Ion Binding Identical Protein Binding
	Biological Process	Protein Targeting To Mitochondrion Response To Muscle Activity TRNA Import Into Mitochondrion Macroautophagy Protein Deubiquitination Protein Import Into Mitochondrial Matrix Mitochondrial Outer Membrane Translocase Complex Assembly Response To 3,3',5-triiodo-L-thyronine	Urea Cycle Liver Development Ornithine Catabolic Process Midgut Development Response To Zinc Ion Citrulline Biosynthetic Process Response To Insulin Arginine Biosynthetic Process Via Ornithine Anion Homeostasis Response To Biotin Ammonia Homeostasis
Pathways		Mitochondrial protein import Pink/Parkin Mediated Mitophagy Ub-specific processing proteases	Mitochondrial protein import Mitochondrial protein import Urea cycle
Drugs			Ornithine L-Citrulline N-(Phosphonoacetyl)-L-Ornithine Norvaline
Diseases			Ornithine transcarbamylase deficiency
GWAS		Cholesterol, total ( 20686565) Cobalt levels ( 26025379) Immune reponse to smallpox (secreted IL-2) ( 22610502) LDL cholesterol ( 20686565) Night sleep phenotypes ( 27126917) Obesity-related traits ( 23251661)
Interacting Genes		19 interacting genes: AIP APOA1 ATXN1 BAG6 BCL2 CDC73 CEP126 DHFR FBXO7 FEZ1 HAP1 HSD17B10 OTC PPHLN1 PTN TOMM22 TOMM40 UCP1 VDAC1	1 interacting genes: TOMM20
Entrez ID		9804	5009
HPRD ID		03507	08947
Ensembl ID		ENSG00000173726	ENSG00000036473
Uniprot IDs		A0A024R3W2 Q15388	P00480
PDB IDs		4APO	1C9Y 1EP9 1FVO 1OTH
Enriched GO Terms of Interacting Partners?
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