OTC and TOMM20

Number of citations of the paper that reports this interaction (PubMedID 9756929)
10

Data Source:
BioGRID (pull down)
HPRD (in vitro)

		OTC	TOMM20
Description		ornithine carbamoyltransferase	translocase of outer mitochondrial membrane 20
Image
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Matrix Intracellular Membrane-bounded Organelle	Mitochondrion Mitochondrial Outer Membrane Mitochondrial Outer Membrane Translocase Complex Integral Component Of Mitochondrial Outer Membrane Mitochondria-associated ER Membrane
	Molecular Function	Ornithine Carbamoyltransferase Activity Phospholipid Binding Amino Acid Binding Phosphate Ion Binding Identical Protein Binding	Protein Binding P-P-bond-hydrolysis-driven Protein Transmembrane Transporter Activity Mitochondrion Targeting Sequence Binding Unfolded Protein Binding
	Biological Process	Urea Cycle Liver Development Ornithine Catabolic Process Midgut Development Response To Zinc Ion Citrulline Biosynthetic Process Response To Insulin Arginine Biosynthetic Process Via Ornithine Anion Homeostasis Response To Biotin Ammonia Homeostasis	Protein Targeting To Mitochondrion Response To Muscle Activity TRNA Import Into Mitochondrion Macroautophagy Protein Deubiquitination Protein Import Into Mitochondrial Matrix Mitochondrial Outer Membrane Translocase Complex Assembly Response To 3,3',5-triiodo-L-thyronine
Pathways		Mitochondrial protein import Mitochondrial protein import Urea cycle	Mitochondrial protein import Pink/Parkin Mediated Mitophagy Ub-specific processing proteases
Drugs		Ornithine L-Citrulline N-(Phosphonoacetyl)-L-Ornithine Norvaline
Diseases		Ornithine transcarbamylase deficiency
GWAS			Cholesterol, total ( 20686565) Cobalt levels ( 26025379) Immune reponse to smallpox (secreted IL-2) ( 22610502) LDL cholesterol ( 20686565) Night sleep phenotypes ( 27126917) Obesity-related traits ( 23251661)
Interacting Genes		1 interacting genes: TOMM20	19 interacting genes: AIP APOA1 ATXN1 BAG6 BCL2 CDC73 CEP126 DHFR FBXO7 FEZ1 HAP1 HSD17B10 OTC PPHLN1 PTN TOMM22 TOMM40 UCP1 VDAC1
Entrez ID		5009	9804
HPRD ID		08947	03507
Ensembl ID		ENSG00000036473	ENSG00000173726
Uniprot IDs		P00480	A0A024R3W2 Q15388
PDB IDs		1C9Y 1EP9 1FVO 1OTH	4APO
Enriched GO Terms of Interacting Partners?
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