TOMM20 and PPHLN1

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		TOMM20	PPHLN1
Description		translocase of outer mitochondrial membrane 20	periphilin 1
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Outer Membrane Mitochondrial Outer Membrane Translocase Complex Integral Component Of Mitochondrial Outer Membrane Mitochondria-associated ER Membrane	Nucleoplasm Chromosome Golgi Apparatus Cytosol
	Molecular Function	Protein Binding P-P-bond-hydrolysis-driven Protein Transmembrane Transporter Activity Mitochondrion Targeting Sequence Binding Unfolded Protein Binding	RNA Binding Protein Binding
	Biological Process	Protein Targeting To Mitochondrion Response To Muscle Activity TRNA Import Into Mitochondrion Macroautophagy Protein Deubiquitination Protein Import Into Mitochondrial Matrix Mitochondrial Outer Membrane Translocase Complex Assembly Response To 3,3',5-triiodo-L-thyronine	Keratinization Negative Regulation Of Gene Expression, Epigenetic Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Methylation-dependent Chromatin Silencing Protein Localization To Heterochromatin
Pathways		Mitochondrial protein import Pink/Parkin Mediated Mitophagy Ub-specific processing proteases
Drugs
Diseases
GWAS		Cholesterol, total ( 20686565) Cobalt levels ( 26025379) Immune reponse to smallpox (secreted IL-2) ( 22610502) LDL cholesterol ( 20686565) Night sleep phenotypes ( 27126917) Obesity-related traits ( 23251661)	Coronary artery disease ( 29212778) Diastolic blood pressure ( 30224653)
Interacting Genes		19 interacting genes: AIP APOA1 ATXN1 BAG6 BCL2 CDC73 CEP126 DHFR FBXO7 FEZ1 HAP1 HSD17B10 OTC PPHLN1 PTN TOMM22 TOMM40 UCP1 VDAC1	24 interacting genes: APP BCL2L1 BRCA1 CASP5 CCDC57 CDC37 CDK6 CLK1 FBXO7 MTUS2 NAGK PAXIP1 PPL SEPTIN8 SNCAIP SQSTM1 SRPK2 TGM2 TOMM20 TOPBP1 TP53BP2 TSGA10 UFD1 VIM
Entrez ID		9804	51535
HPRD ID		03507	10488
Ensembl ID		ENSG00000173726	ENSG00000134283
Uniprot IDs		A0A024R3W2 Q15388	Q8NEY8
PDB IDs		4APO
Enriched GO Terms of Interacting Partners?
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