CD53 and GGT1

Number of citations of the paper that reports this interaction (PubMedID 9862348)
9

Data Source:
HPRD (in vivo)

		CD53	GGT1
Description		CD53 molecule	gamma-glutamyltransferase 1
Image		No pdb structure
GO Annotations	Cellular Component	Immunological Synapse Plasma Membrane Integral Component Of Plasma Membrane Cell-cell Junction Cell Surface Specific Granule Membrane Extracellular Exosome Tertiary Granule Membrane	Extracellular Space Plasma Membrane Integral Component Of Membrane Extracellular Exosome
	Molecular Function	Protein Binding	Peptidyltransferase Activity Leukotriene-C(4) Hydrolase Protein Binding Glutathione Hydrolase Activity Hypoglycin A Gamma-glutamyl Transpeptidase Activity Leukotriene C4 Gamma-glutamyl Transferase Activity
	Biological Process	Signal Transduction Neutrophil Degranulation Positive Regulation Of Myoblast Fusion	Regulation Of Immune System Process Translation Proteolysis Cellular Amino Acid Metabolic Process Glutamate Metabolic Process Fatty Acid Metabolic Process Leukotriene Metabolic Process Glutathione Biosynthetic Process Glutathione Catabolic Process Xenobiotic Metabolic Process Spermatogenesis Cysteine Biosynthetic Process Peptide Modification Zymogen Activation Response To Estradiol Response To Lipopolysaccharide Response To Tumor Necrosis Factor Regulation Of Inflammatory Response Leukotriene D4 Biosynthetic Process
Pathways		Neutrophil degranulation	Glutathione synthesis and recycling Synthesis of Leukotrienes (LT) and Eoxins (EX) Aflatoxin activation and detoxification Defective GGT1 causes Glutathionuria (GLUTH) Defective GGT1 causes Glutathionuria (GLUTH) LTC4-CYSLTR mediated IL4 production
Drugs			Glutathione
Diseases
GWAS		Cytomegalovirus antibody response ( 21993531) Obesity-related traits ( 23251661)	Acne (severe) ( 24927181) Blood metabolite levels ( 24816252) Blood protein levels ( 23696881) Gamma glutamyl transferase levels ( 29403010) Gamma glutamyl transpeptidase ( 21909109) Hematological and biochemical traits ( 20139978) Liver enzyme levels ( 18940312) Liver enzyme levels (gamma-glutamyl transferase) ( 22001757) Protein quantitative trait loci ( 18464913) Serum metabolite levels ( 23093944) Urinary metabolite levels in chronic kidney disease ( 31959995) Urinary metabolite modules (eigenmetabolites) in chronic kidney disease ( 31959995)
Interacting Genes		6 interacting genes: CD2 CD4 CD9 GGT1 IL2 IL4	3 interacting genes: CD53 KCNMA1 NAMPT
Entrez ID		963	2678
HPRD ID		01054	01980
Ensembl ID		ENSG00000143119	ENSG00000100031
Uniprot IDs		B4DQB5 P19397	A0A140VJJ9 P19440
PDB IDs			4GDX 4GG2 4Z9O 4ZBK 4ZC6 4ZCG 5V4Q
Enriched GO Terms of Interacting Partners?
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