GGT1 and CD53

Number of citations of the paper that reports this interaction (PubMedID 9862348)
9

Data Source:
HPRD (in vivo)

		GGT1	CD53
Description		gamma-glutamyltransferase 1	CD53 molecule
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Space Plasma Membrane Integral Component Of Membrane Extracellular Exosome	Immunological Synapse Plasma Membrane Integral Component Of Plasma Membrane Cell-cell Junction Cell Surface Specific Granule Membrane Extracellular Exosome Tertiary Granule Membrane
	Molecular Function	Peptidyltransferase Activity Leukotriene-C(4) Hydrolase Protein Binding Glutathione Hydrolase Activity Hypoglycin A Gamma-glutamyl Transpeptidase Activity Leukotriene C4 Gamma-glutamyl Transferase Activity	Protein Binding
	Biological Process	Regulation Of Immune System Process Translation Proteolysis Cellular Amino Acid Metabolic Process Glutamate Metabolic Process Fatty Acid Metabolic Process Leukotriene Metabolic Process Glutathione Biosynthetic Process Glutathione Catabolic Process Xenobiotic Metabolic Process Spermatogenesis Cysteine Biosynthetic Process Peptide Modification Zymogen Activation Response To Estradiol Response To Lipopolysaccharide Response To Tumor Necrosis Factor Regulation Of Inflammatory Response Leukotriene D4 Biosynthetic Process	Signal Transduction Neutrophil Degranulation Positive Regulation Of Myoblast Fusion
Pathways		Glutathione synthesis and recycling Synthesis of Leukotrienes (LT) and Eoxins (EX) Aflatoxin activation and detoxification Defective GGT1 causes Glutathionuria (GLUTH) Defective GGT1 causes Glutathionuria (GLUTH) LTC4-CYSLTR mediated IL4 production	Neutrophil degranulation
Drugs		Glutathione
Diseases
GWAS		Acne (severe) ( 24927181) Blood metabolite levels ( 24816252) Blood protein levels ( 23696881) Gamma glutamyl transferase levels ( 29403010) Gamma glutamyl transpeptidase ( 21909109) Hematological and biochemical traits ( 20139978) Liver enzyme levels ( 18940312) Liver enzyme levels (gamma-glutamyl transferase) ( 22001757) Protein quantitative trait loci ( 18464913) Serum metabolite levels ( 23093944) Urinary metabolite levels in chronic kidney disease ( 31959995) Urinary metabolite modules (eigenmetabolites) in chronic kidney disease ( 31959995)	Cytomegalovirus antibody response ( 21993531) Obesity-related traits ( 23251661)
Interacting Genes		3 interacting genes: CD53 KCNMA1 NAMPT	6 interacting genes: CD2 CD4 CD9 GGT1 IL2 IL4
Entrez ID		2678	963
HPRD ID		01980	01054
Ensembl ID		ENSG00000100031	ENSG00000143119
Uniprot IDs		A0A140VJJ9 P19440	B4DQB5 P19397
PDB IDs		4GDX 4GG2 4Z9O 4ZBK 4ZC6 4ZCG 5V4Q
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?