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TAOK2 and TUBB
Number of citations of the paper that reports this interaction (PubMedID
12639963
)
20
Data Source:
BioGRID
(pull down)
HPRD
(in vitro)
TAOK2
TUBB
Description
TAO kinase 2
tubulin beta class I
Image
No pdb structure
GO Annotations
Cellular Component
Nucleoplasm
Nucleolus
Cytoplasm
Cytosol
Actin Cytoskeleton
Integral Component Of Membrane
Axon
Cytoplasmic Vesicle Membrane
Cytoplasmic Vesicle
Neuron Projection
Receptor Complex
Dendritic Growth Cone
Axonal Growth Cone
Extracellular Region
Nucleus
Nuclear Envelope Lumen
Cytoplasm
Cytoskeleton
Microtubule
Protein-containing Complex
Azurophil Granule Lumen
Cytoplasmic Ribonucleoprotein Granule
Cell Body
Membrane Raft
Extracellular Exosome
Molecular Function
Protein Serine/threonine Kinase Activity
MAP Kinase Kinase Kinase Activity
ATP Binding
Mitogen-activated Protein Kinase Kinase Binding
Neuropilin Binding
Tau Protein Binding
Tau-protein Kinase Activity
GTPase Activity
Structural Molecule Activity
Structural Constituent Of Cytoskeleton
Protein Binding
GTP Binding
Protein Domain Specific Binding
Ubiquitin Protein Ligase Binding
GTPase Activating Protein Binding
MHC Class I Protein Binding
Protein-containing Complex Binding
Biological Process
Activation Of MAPKK Activity
Activation Of MAPK Activity
Regulation Of Cell Growth
Protein Targeting To Membrane
Apoptotic Process
Cellular Response To DNA Damage Stimulus
Mitotic G2 DNA Damage Checkpoint
Regulation Of Mitotic Cell Cycle
Axonogenesis
Regulation Of Cell Shape
Cell Migration
Signal Transduction By Protein Phosphorylation
Actin Cytoskeleton Organization
Stress-activated Protein Kinase Signaling Cascade
G2 DNA Damage Checkpoint
Positive Regulation Of Protein Autophosphorylation
Activation Of Protein Kinase Activity
Positive Regulation Of Stress-activated MAPK Cascade
Regulation Of Actin Cytoskeleton Organization
Positive Regulation Of JNK Cascade
Protein Autophosphorylation
Focal Adhesion Assembly
Stress-activated MAPK Cascade
Basal Dendrite Morphogenesis
Basal Dendrite Arborization
G2/M Transition Of Mitotic Cell Cycle
Microtubule Cytoskeleton Organization
Mitotic Cell Cycle
Microtubule-based Process
Cellular Process
Regulation Of G2/M Transition Of Mitotic Cell Cycle
Cytoskeleton-dependent Intracellular Transport
Natural Killer Cell Mediated Cytotoxicity
Neutrophil Degranulation
Regulation Of Synapse Organization
Spindle Assembly
Cell Division
Ciliary Basal Body-plasma Membrane Docking
Pathways
Regulation of PLK1 Activity at G2/M Transition
Loss of Nlp from mitotic centrosomes
Recruitment of mitotic centrosome proteins and complexes
Loss of proteins required for interphase microtubule organization from the centrosome
Recruitment of NuMA to mitotic centrosomes
Anchoring of the basal body to the plasma membrane
Neutrophil degranulation
AURKA Activation by TPX2
Drugs
Dexfosfoserine
Vinorelbine
Vincristine
Vinblastine
Podofilox
Colchicine
Epothilone D
Patupilone
CYT997
CA4P
ZEN-012
Copper
Depatuxizumab mafodotin
Milataxel
Diseases
GWAS
Autism spectrum disorder or schizophrenia (
28540026
)
Body fat distribution (arm fat ratio) (
30664634
)
Body mass index (
29273807
)
Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) (
30940143
)
Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) (
31374203
)
Metabolic syndrome (
31589552
)
Schizophrenia (
28991256
25056061
29483656
30285260
)
Autism spectrum disorder or schizophrenia (
28540026
)
Blood protein levels (
28240269
)
Decreased fine motor function in Charcot-Marie-Tooth disease 1A (eating with utensils) (
30958311
)
Handedness (non-right-handed vs right-handed) (
31504236
)
Interacting Genes
12 interacting genes:
BCKDK
ELK1
KLHL12
MAP2K3
MAP2K6
MEGF10
RCHY1
TLE3
TUBA1A
TUBA4A
TUBB
USF1
71 interacting genes:
ADAP2
ALDOA
APP
ARL8B
ATXN3
B4GALT1
BMPR2
BRCA1
CDKN2A
CLIP1
CMTM5
CNN1
CRIPT
DISC1
DPYSL2
DYNLL1
ESR1
GDAP1
GRM1
HDAC6
HGS
HTRA2
HTT
LNX2
MAGEA2B
MAL2
MAP1A
MAP3K10
MAP4
MAP6
MAPRE1
MAPT
MARK4
MRGBP
MTNR1A
MX1
NCALD
NCAM1
NCAPH2
NDEL1
NPHP1
PFDN4
PLK1
PRKN
PTEN
RAB8B
RACK1
RASSF1
S100A8
S100A9
SDC3
SPP1
STAU1
SUMO2
SYT9
TAOK2
TBCD
TGM2
TINF2
TPPP
TTBK1
TTK
TUBA1A
VAV1
YWHAB
YWHAG
YWHAQ
YWHAZ
ZAP70
ZFYVE21
ZMYND19
Entrez ID
9344
203068
HPRD ID
18147
01852
Ensembl ID
ENSG00000149930
ENSG00000196230
Uniprot IDs
Q9UL54
B4DMJ5
B4DQN9
B4DY90
P07437
Q5ST81
Q5SU16
PDB IDs
3QNZ
3QO0
5N5N
6I2I
6QUS
6QUY
6QVJ
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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