TAOK2 and MEGF10

Number of citations of the paper that reports this interaction (PubMedID 12421765)
39

Data Source:
HPRD (two hybrid)

		TAOK2	MEGF10
Description		TAO kinase 2	multiple EGF like domains 10
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Nucleolus Cytoplasm Cytosol Actin Cytoskeleton Integral Component Of Membrane Axon Cytoplasmic Vesicle Membrane Cytoplasmic Vesicle Neuron Projection Receptor Complex Dendritic Growth Cone Axonal Growth Cone	Phagocytic Cup Plasma Membrane Integral Component Of Membrane Cell Projection
	Molecular Function	Protein Serine/threonine Kinase Activity MAP Kinase Kinase Kinase Activity ATP Binding Mitogen-activated Protein Kinase Kinase Binding Neuropilin Binding Tau Protein Binding Tau-protein Kinase Activity	Complement Component C1q Binding Scavenger Receptor Activity Notch Binding
	Biological Process	Activation Of MAPKK Activity Activation Of MAPK Activity Regulation Of Cell Growth Protein Targeting To Membrane Apoptotic Process Cellular Response To DNA Damage Stimulus Mitotic G2 DNA Damage Checkpoint Regulation Of Mitotic Cell Cycle Axonogenesis Regulation Of Cell Shape Cell Migration Signal Transduction By Protein Phosphorylation Actin Cytoskeleton Organization Stress-activated Protein Kinase Signaling Cascade G2 DNA Damage Checkpoint Positive Regulation Of Protein Autophosphorylation Activation Of Protein Kinase Activity Positive Regulation Of Stress-activated MAPK Cascade Regulation Of Actin Cytoskeleton Organization Positive Regulation Of JNK Cascade Protein Autophosphorylation Focal Adhesion Assembly Stress-activated MAPK Cascade Basal Dendrite Morphogenesis Basal Dendrite Arborization	Skeletal Muscle Satellite Cell Activation Skeletal Muscle Satellite Cell Differentiation Skeletal Muscle Satellite Cell Proliferation Positive Regulation Of Cell-cell Adhesion Muscle Cell Proliferation Homotypic Cell-cell Adhesion Apoptotic Cell Clearance Engulfment Of Apoptotic Cell Recognition Of Apoptotic Cell Myoblast Development Regulation Of Skeletal Muscle Tissue Development Regulation Of Muscle Cell Differentiation Myoblast Migration Muscle Cell Development Apoptotic Process Involved In Development Positive Regulation Of Myoblast Proliferation
Pathways
Drugs		Dexfosfoserine
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Body fat distribution (arm fat ratio) ( 30664634) Body mass index ( 29273807) Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Metabolic syndrome ( 31589552) Schizophrenia ( 28991256 25056061 29483656 30285260)	Alzheimer's disease (cognitive decline) ( 23535033) Bone mineral content ( 31790847) Chromosomal aberration frequency (chromosome type) in genotoxic compound exposure ( 31586183) Hearing loss in Charcot-Marie-Tooth disease 1A ( 30958311) Initial pursuit acceleration ( 29064472) Response to antipsychotic treatment in schizophrenia ( 29503163)
Interacting Genes		12 interacting genes: BCKDK ELK1 KLHL12 MAP2K3 MAP2K6 MEGF10 RCHY1 TLE3 TUBA1A TUBA4A TUBB USF1	22 interacting genes: AARS2 ALMS1 AP2M1 ARHGAP32 BAHD1 CADPS2 CEP57 CUL7 DHX16 GRB10 HDAC4 ITSN2 MCF2L2 RANBP10 SART3 SCAPER SHTN1 SNRNP200 TAOK2 TMEM132A VWA8 ZNFX1
Entrez ID		9344	84466
HPRD ID		18147	14384
Ensembl ID		ENSG00000149930	ENSG00000145794
Uniprot IDs		Q9UL54	Q96KG7
PDB IDs
Enriched GO Terms of Interacting Partners?
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