GTF3C3 and PCBD1

Number of citations of the paper that reports this interaction (PubMedID 20211142)
329

Data Source:
BioGRID (two hybrid)

		GTF3C3	PCBD1
Description		general transcription factor IIIC subunit 3	pterin-4 alpha-carbinolamine dehydratase 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Transcription Factor TFIIIC Complex Nucleoplasm Nucleolus Nuclear Membrane	Nucleoplasm Cytosol Extracellular Exosome
	Molecular Function	DNA Binding Protein Binding	Transcription Coactivator Activity Phenylalanine 4-monooxygenase Activity Protein Binding 4-alpha-hydroxytetrahydrobiopterin Dehydratase Activity Identical Protein Binding
	Biological Process	Transcription By RNA Polymerase III 5S Class RRNA Transcription By RNA Polymerase III TRNA Transcription By RNA Polymerase III RNA Polymerase III Preinitiation Complex Assembly	L-phenylalanine Catabolic Process Tetrahydrobiopterin Biosynthetic Process Regulation Of Protein Binding Positive Regulation Of Transcription, DNA-templated Oxidation-reduction Process
Pathways		RNA Polymerase III Abortive And Retractive Initiation RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter	Phenylalanine metabolism
Drugs			L-erythro-7,8-dihydrobiopterin
Diseases			Phenylketonuria (PKU); Hyperphenylalaninemia, BH4-deficient
GWAS			Blood protein levels ( 30072576) Chronotype ( 30696823) Immature fraction of reticulocytes ( 27863252) Microalbuminuria ( 26631737) Obesity-related traits ( 23251661)
Interacting Genes		7 interacting genes: BRF1 DEDD DEDD2 GTF3C5 HNRNPD PCBD1 TBP	49 interacting genes: ACIN1 APP BRD7 CACNA1C CALCOCO1 CDK5RAP2 CEBPZ DENND4A DIP2C DVL2 DYRK1B EHMT1 FXR2 GORASP2 GTF3C3 HES4 HNF1A HNF4A KLF13 LNX1 MIS18BP1 NFKB1 NIF3L1 NTAQ1 NUDT18 PAH PAPOLG PCBD2 POLR3A RBL2 RPS24 SAP30 SCMH1 SMARCD1 SOWAHC SUPT5H TFF3 TIMELESS TRIM5 WWP1 ZBTB25 ZNF195 ZNF202 ZNF23 ZNF263 ZNF451 ZNF567 ZNF688 ZNF714
Entrez ID		9330	5092
HPRD ID		11997	00523
Ensembl ID		ENSG00000119041	ENSG00000166228
Uniprot IDs		Q9Y5Q9	P61457
PDB IDs
Enriched GO Terms of Interacting Partners?
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