PCBD1 and TFF3

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		PCBD1	TFF3
Description		pterin-4 alpha-carbinolamine dehydratase 1	trefoil factor 3
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytosol Extracellular Exosome	Extracellular Region Extracellular Space Secretory Granule
	Molecular Function	Transcription Coactivator Activity Phenylalanine 4-monooxygenase Activity Protein Binding 4-alpha-hydroxytetrahydrobiopterin Dehydratase Activity Identical Protein Binding	Molecular_function Protein Binding
	Biological Process	L-phenylalanine Catabolic Process Tetrahydrobiopterin Biosynthetic Process Regulation Of Protein Binding Positive Regulation Of Transcription, DNA-templated Oxidation-reduction Process	Regulation Of Glucose Metabolic Process Maintenance Of Gastrointestinal Epithelium
Pathways		Phenylalanine metabolism	Estrogen-dependent gene expression
Drugs		L-erythro-7,8-dihydrobiopterin
Diseases		Phenylketonuria (PKU); Hyperphenylalaninemia, BH4-deficient
GWAS		Blood protein levels ( 30072576) Chronotype ( 30696823) Immature fraction of reticulocytes ( 27863252) Microalbuminuria ( 26631737) Obesity-related traits ( 23251661)	Spatial memory ( 31596458)
Interacting Genes		49 interacting genes: ACIN1 APP BRD7 CACNA1C CALCOCO1 CDK5RAP2 CEBPZ DENND4A DIP2C DVL2 DYRK1B EHMT1 FXR2 GORASP2 GTF3C3 HES4 HNF1A HNF4A KLF13 LNX1 MIS18BP1 NFKB1 NIF3L1 NTAQ1 NUDT18 PAH PAPOLG PCBD2 POLR3A RBL2 RPS24 SAP30 SCMH1 SMARCD1 SOWAHC SUPT5H TFF3 TIMELESS TRIM5 WWP1 ZBTB25 ZNF195 ZNF202 ZNF23 ZNF263 ZNF451 ZNF567 ZNF688 ZNF714	3 interacting genes: PCBD1 SGTA ZSCAN9
Entrez ID		5092	7033
HPRD ID		00523	02797
Ensembl ID		ENSG00000166228	ENSG00000160180
Uniprot IDs		P61457	Q07654
PDB IDs			1E9T 1PE3
Enriched GO Terms of Interacting Partners?
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