GTF3C3 and BRF1

Number of citations of the paper that reports this interaction (PubMedID 10373544)
27

Data Source:
HPRD (in vitro, in vivo)

		GTF3C3	BRF1
Description		general transcription factor IIIC subunit 3	BRF1 RNA polymerase III transcription initiation factor subunit
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Transcription Factor TFIIIC Complex Nucleoplasm Nucleolus Nuclear Membrane	Transcription Factor TFIIIB Complex Nucleus Nucleoplasm
	Molecular Function	DNA Binding Protein Binding	RNA Polymerase III Type 3 Promoter Sequence-specific DNA Binding Protein Binding Transcription Factor Binding TBP-class Protein Binding Metal Ion Binding
	Biological Process	Transcription By RNA Polymerase III 5S Class RRNA Transcription By RNA Polymerase III TRNA Transcription By RNA Polymerase III RNA Polymerase III Preinitiation Complex Assembly	DNA-templated Transcription, Initiation Transcription By RNA Polymerase III Transcription Initiation From RNA Polymerase III Promoter RRNA Transcription TRNA Transcription Positive Regulation Of Transcription By RNA Polymerase III RNA Polymerase III Preinitiation Complex Assembly
Pathways		RNA Polymerase III Abortive And Retractive Initiation RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter	RNA Polymerase III Abortive And Retractive Initiation RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter
Drugs
Diseases
GWAS			Huntington's disease progression ( 28642124) Mean platelet volume ( 22139419 27863252) Platelet count ( 29403010 27863252) Platelet distribution width ( 27863252)
Interacting Genes		7 interacting genes: BRF1 DEDD DEDD2 GTF3C5 HNRNPD PCBD1 TBP	16 interacting genes: APP CSNK2A1 DTNBP1 GTF3C3 GTF3C4 GTF3C5 PCBD2 POLR3F RB1 RBL1 RBL2 RHOU RLIM TBP TP53 UBC
Entrez ID		9330	2972
HPRD ID		11997	05361
Ensembl ID		ENSG00000119041	ENSG00000185024
Uniprot IDs		Q9Y5Q9	A0A024R6P8 Q92994 V9HVY2
PDB IDs
Enriched GO Terms of Interacting Partners?
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