PCBD1 and ZNF688

Number of citations of the paper that reports this interaction (PubMedID 26871637)
108

Data Source:
BioGRID (two hybrid)

		PCBD1	ZNF688
Description		pterin-4 alpha-carbinolamine dehydratase 1	zinc finger protein 688
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytosol Extracellular Exosome	Cellular_component Nucleus
	Molecular Function	Transcription Coactivator Activity Phenylalanine 4-monooxygenase Activity Protein Binding 4-alpha-hydroxytetrahydrobiopterin Dehydratase Activity Identical Protein Binding	Molecular_function DNA-binding Transcription Factor Activity Sequence-specific DNA Binding Metal Ion Binding
	Biological Process	L-phenylalanine Catabolic Process Tetrahydrobiopterin Biosynthetic Process Regulation Of Protein Binding Positive Regulation Of Transcription, DNA-templated Oxidation-reduction Process	Regulation Of Transcription, DNA-templated Biological_process
Pathways		Phenylalanine metabolism	Generic Transcription Pathway
Drugs		L-erythro-7,8-dihydrobiopterin
Diseases		Phenylketonuria (PKU); Hyperphenylalaninemia, BH4-deficient
GWAS		Blood protein levels ( 30072576) Chronotype ( 30696823) Immature fraction of reticulocytes ( 27863252) Microalbuminuria ( 26631737) Obesity-related traits ( 23251661)
Interacting Genes		49 interacting genes: ACIN1 APP BRD7 CACNA1C CALCOCO1 CDK5RAP2 CEBPZ DENND4A DIP2C DVL2 DYRK1B EHMT1 FXR2 GORASP2 GTF3C3 HES4 HNF1A HNF4A KLF13 LNX1 MIS18BP1 NFKB1 NIF3L1 NTAQ1 NUDT18 PAH PAPOLG PCBD2 POLR3A RBL2 RPS24 SAP30 SCMH1 SMARCD1 SOWAHC SUPT5H TFF3 TIMELESS TRIM5 WWP1 ZBTB25 ZNF195 ZNF202 ZNF23 ZNF263 ZNF451 ZNF567 ZNF688 ZNF714	70 interacting genes: ABI2 BEND5 BLZF1 CADPS CALCOCO2 CARD9 CBY2 CCDC136 CCDC33 CCDC57 CEP44 CEP70 CEP72 CRX EHMT2 FBXO7 FCHO1 FHL5 GMPPA GOLGA2 GPRASP2 HMBOX1 HNRNPK HOMEZ IHO1 KHDRBS2 KHDRBS3 KIFC3 KRT13 KRT15 KRT31 KRT40 KRTAP10-3 KRTAP10-9 KRTAP12-2 KRTAP4-2 LDOC1 MAGED1 MDFI MEOX2 MID2 MIPOL1 MKRN3 NOTCH2NLA PCBD1 PLSCR1 PNMA1 PNMA2 PSMA3 PSTPIP1 REL RFX6 RINT1 RPGRIP1 SPAG5 SSX2IP TADA2A TCF12 TCF4 TMCC2 TNS2 TRAF1 TRAF2 TRAF4 TRIM23 TRIM27 TRIP6 USHBP1 WWP2 ZC4H2
Entrez ID		5092	146542
HPRD ID		00523	14070
Ensembl ID		ENSG00000166228	ENSG00000229809
Uniprot IDs		P61457	A0A024QZB6 A0A0S2Z633 P0C7X2
PDB IDs
Enriched GO Terms of Interacting Partners?
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