EIF2B3 and STC2

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		EIF2B3	STC2
Description		eukaryotic translation initiation factor 2B subunit gamma	stanniocalcin 2
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Eukaryotic Translation Initiation Factor 2B Complex Guanyl-nucleotide Exchange Factor Complex	Extracellular Space Cell Endoplasmic Reticulum Endoplasmic Reticulum Lumen Golgi Apparatus Perinuclear Region Of Cytoplasm
	Molecular Function	Translation Initiation Factor Activity Guanyl-nucleotide Exchange Factor Activity Protein Binding Translation Factor Activity, RNA Binding Nucleotidyltransferase Activity	Hormone Activity Enzyme Binding Heme Binding Protein Homodimerization Activity
	Biological Process	Cytoplasmic Translational Initiation Translational Initiation Response To Heat Response To Glucose Oligodendrocyte Development Hippocampus Development Response To Peptide Hormone T Cell Receptor Signaling Pathway	Cellular Calcium Ion Homeostasis Response To Oxidative Stress Embryo Implantation Negative Regulation Of Gene Expression Endoplasmic Reticulum Unfolded Protein Response Response To Vitamin D Negative Regulation Of Multicellular Organism Growth Response To Peptide Hormone Post-translational Protein Modification Cellular Protein Metabolic Process Decidualization Regulation Of Hormone Biosynthetic Process Cellular Response To Hypoxia Regulation Of Store-operated Calcium Entry
Pathways		Recycling of eIF2:GDP	Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation
Drugs
Diseases		Leukoencephalopathy with vanishing white matter; Vanishing white matter disease; Childhood ataxia with diffuse central nervous system hypomyelination (CACH); Cree leukoencephalopathy (CLE)
GWAS			Antipsychotic drug-induced weight gain in schizophrenia ( 31447353) Atrial fibrillation ( 29892015) Birth weight ( 31043758) Height ( 25429064 31562340) Immunoglobulin A vasculitis ( 28698626) Prostate cancer ( 23535732) Urate levels in overweight individuals ( 25811787)
Interacting Genes		5 interacting genes: EIF2S1 EIF2S2 GOLM1 NDUFB8 STC2	20 interacting genes: ADAM11 AIFM1 ARHGEF40 ARRB2 CARHSP1 CELF6 CPN1 EIF2B3 ELOB ERGIC1 FAF2 FGFR4 HK3 PEBP1 PLA2G5 POLR2C POLR3F PPP1R8 PTN RNF44
Entrez ID		8891	8614
HPRD ID		09379	04717
Ensembl ID		ENSG00000070785	ENSG00000113739
Uniprot IDs		Q9HA31 Q9NR50	O76061 Q6FHC9
PDB IDs		6CAJ 6EZO 6K71 6K72 6O81 6O85 6O9Z
Enriched GO Terms of Interacting Partners?
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