STC2 and POLR2C

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
HPRD (two hybrid)

		STC2	POLR2C
Description		stanniocalcin 2	RNA polymerase II subunit C
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space Cell Endoplasmic Reticulum Endoplasmic Reticulum Lumen Golgi Apparatus Perinuclear Region Of Cytoplasm	Nucleus Nucleoplasm RNA Polymerase II, Core Complex Cytosol Microtubule Cytoskeleton
	Molecular Function	Hormone Activity Enzyme Binding Heme Binding Protein Homodimerization Activity	DNA Binding DNA-directed 5'-3' RNA Polymerase Activity Protein Binding Protein Dimerization Activity
	Biological Process	Cellular Calcium Ion Homeostasis Response To Oxidative Stress Embryo Implantation Negative Regulation Of Gene Expression Endoplasmic Reticulum Unfolded Protein Response Response To Vitamin D Negative Regulation Of Multicellular Organism Growth Response To Peptide Hormone Post-translational Protein Modification Cellular Protein Metabolic Process Decidualization Regulation Of Hormone Biosynthetic Process Cellular Response To Hypoxia Regulation Of Store-operated Calcium Entry	MRNA Splicing, Via Spliceosome Transcription-coupled Nucleotide-excision Repair Transcription, DNA-templated Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Transcription Elongation From RNA Polymerase II Promoter 7-methylguanosine MRNA Capping Fibroblast Growth Factor Receptor Signaling Pathway RNA Metabolic Process Somatic Stem Cell Population Maintenance SnRNA Transcription By RNA Polymerase II Positive Regulation Of Viral Transcription Regulation Of Gene Silencing By MiRNA
Pathways		Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation	Formation of RNA Pol II elongation complex Formation of the Early Elongation Complex Formation of HIV elongation complex in the absence of HIV Tat Formation of the HIV-1 Early Elongation Complex RNA Pol II CTD phosphorylation and interaction with CE during HIV infection HIV Transcription Initiation RNA Polymerase II HIV Promoter Escape Transcription of the HIV genome Formation of HIV-1 elongation complex containing HIV-1 Tat Formation of HIV-1 elongation complex containing HIV-1 Tat Pausing and recovery of Tat-mediated HIV elongation Abortive elongation of HIV-1 transcript in the absence of Tat Tat-mediated HIV elongation arrest and recovery Tat-mediated elongation of the HIV-1 transcript HIV elongation arrest and recovery Pausing and recovery of HIV elongation Viral Messenger RNA Synthesis MicroRNA (miRNA) biogenesis Transcriptional regulation by small RNAs PIWI-interacting RNA (piRNA) biogenesis Activation of anterior HOX genes in hindbrain development during early embryogenesis RNA Polymerase II Pre-transcription Events Formation of TC-NER Pre-Incision Complex Transcription-Coupled Nucleotide Excision Repair (TC-NER) Dual incision in TC-NER Gap-filling DNA repair synthesis and ligation in TC-NER TP53 Regulates Transcription of DNA Repair Genes FGFR2 alternative splicing RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes mRNA Capping mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway Processing of Capped Intron-Containing Pre-mRNA RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription Initiation RNA Polymerase II Transcription Elongation RNA Polymerase II Transcription Initiation And Promoter Clearance RNA Pol II CTD phosphorylation and interaction with CE Signaling by FGFR2 IIIa TM Estrogen-dependent gene expression
Drugs
Diseases
GWAS		Antipsychotic drug-induced weight gain in schizophrenia ( 31447353) Atrial fibrillation ( 29892015) Birth weight ( 31043758) Height ( 25429064 31562340) Immunoglobulin A vasculitis ( 28698626) Prostate cancer ( 23535732) Urate levels in overweight individuals ( 25811787)
Interacting Genes		20 interacting genes: ADAM11 AIFM1 ARHGEF40 ARRB2 CARHSP1 CELF6 CPN1 EIF2B3 ELOB ERGIC1 FAF2 FGFR4 HK3 PEBP1 PLA2G5 POLR2C POLR3F PPP1R8 PTN RNF44	29 interacting genes: ATF4 ATF7IP C11orf58 CCHCR1 EEF1A1 ERG28 ITCH LRIF1 MYOG NECAB2 NEDD4 NFKBIA NUDT21 OTUD5 POLR2A POLR2B POLR2D POLR2E POLR2F POLR2G POLR2H POLR2J POLR2K POLR2L SMARCC2 STC2 TAF15 UBC UBE2W
Entrez ID		8614	5432
HPRD ID		04717	15945
Ensembl ID		ENSG00000113739	ENSG00000102978
Uniprot IDs		O76061 Q6FHC9	P19387 Q6FGR6
PDB IDs			5IY6 5IY7 5IY8 5IY9 5IYA 5IYB 5IYC 5IYD 6DRD 6O9L
Enriched GO Terms of Interacting Partners?
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