EIF2B3 and NDUFB8

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		EIF2B3	NDUFB8
Description		eukaryotic translation initiation factor 2B subunit gamma	NADH:ubiquinone oxidoreductase subunit B8
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GO Annotations	Cellular Component	Cytoplasm Cytosol Eukaryotic Translation Initiation Factor 2B Complex Guanyl-nucleotide Exchange Factor Complex	Mitochondrial Inner Membrane Mitochondrial Respiratory Chain Complex I Mitochondrial Matrix Endoplasmic Reticulum Integral Component Of Membrane
	Molecular Function	Translation Initiation Factor Activity Guanyl-nucleotide Exchange Factor Activity Protein Binding Translation Factor Activity, RNA Binding Nucleotidyltransferase Activity	NADH Dehydrogenase (ubiquinone) Activity
	Biological Process	Cytoplasmic Translational Initiation Translational Initiation Response To Heat Response To Glucose Oligodendrocyte Development Hippocampus Development Response To Peptide Hormone T Cell Receptor Signaling Pathway	Mitochondrial Electron Transport, NADH To Ubiquinone Mitochondrial Respiratory Chain Complex I Assembly
Pathways		Recycling of eIF2:GDP	Mitochondrial protein import Mitochondrial protein import Respiratory electron transport Complex I biogenesis
Drugs			NADH
Diseases		Leukoencephalopathy with vanishing white matter; Vanishing white matter disease; Childhood ataxia with diffuse central nervous system hypomyelination (CACH); Cree leukoencephalopathy (CLE)
GWAS			Palmitoleic acid (16:1n-7) levels ( 23362303)
Interacting Genes		5 interacting genes: EIF2S1 EIF2S2 GOLM1 NDUFB8 STC2	6 interacting genes: ATP6V0D2 CACNA1A EIF2B3 PFN2 PIM2 ZAP70
Entrez ID		8891	4714
HPRD ID		09379	11886
Ensembl ID		ENSG00000070785	ENSG00000166136
Uniprot IDs		Q9HA31 Q9NR50	O95169
PDB IDs		6CAJ 6EZO 6K71 6K72 6O81 6O85 6O9Z	5XTC 5XTD 5XTH 5XTI
Enriched GO Terms of Interacting Partners?
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