DIRAS3 and BRMS1

Number of citations of the paper that reports this interaction (PubMedID 25640309)
5

Data Source:
BioGRID (two hybrid)

		DIRAS3	BRMS1
Description		DIRAS family GTPase 3	BRMS1 transcriptional repressor and anoikis regulator
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane	Nucleus Nucleoplasm Cytoplasm Sin3-type Complex
	Molecular Function	GTPase Activity Protein Binding GTP Binding GDP Binding	Histone Deacetylase Activity Protein Binding Histone Deacetylase Binding NF-kappaB Binding
	Biological Process	Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Regulation Of Gene Expression By Genetic Imprinting Small GTPase Mediated Signal Transduction	Negative Regulation Of Transcription By RNA Polymerase II Apoptotic Process Histone Deacetylation Negative Regulation Of NF-kappaB Transcription Factor Activity Regulation Of Apoptotic Process Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Protein Deacetylation Positive Regulation Of Anoikis
Pathways			HDACs deacetylate histones
Drugs
Diseases
GWAS			Bipolar disorder ( 21926972 31043756)
Interacting Genes		12 interacting genes: ACADM APC BAG4 BRMS1 CHEK2 FGFR4 KRAS PALB2 PPM1D PTPN1 TGFB1 WT1	48 interacting genes: ANGPTL4 APP ARID4A BEX2 BRMS1L CEP70 CSNK2A1 CYTOR DIRAS3 DNAJB1 DNAJB6 E2F1 EEF1A1 EP300 GOLGB1 HDAC1 HDAC2 HDAC3 HDAC4 HDAC5 HDAC6 HSP90AA1 HSPA4 IL13RA2 ING1 KLK9 KPNA5 LRIF1 LYPD3 MRC2 NMI PFDN5 PSMC3IP RBBP4 RBBP7 RBP1 RELA SAP30 SIN3A SMARCE1 SMTN SNAI1 SNX6 SPOP SUDS3 TAF1 THRSP UBE2D1
Entrez ID		9077	25855
HPRD ID		05547	05879
Ensembl ID		ENSG00000162595	ENSG00000174744
Uniprot IDs		O95661	G5E9I4 Q9HCU9
PDB IDs			2XUS 4AUV
Enriched GO Terms of Interacting Partners?
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