WDR77 and SF1

Number of citations of the paper that reports this interaction (PubMedID 22365833)
132

Data Source:
BioGRID (two hybrid)

		WDR77	SF1
Description		WD repeat domain 77	splicing factor 1
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Golgi Apparatus Cytosol Methylosome	Nucleus Nucleoplasm Spliceosomal Complex Ribosome Nuclear Body
	Molecular Function	Protein Binding Methyl-CpG Binding Nuclear Receptor Transcription Coactivator Activity	Transcription Corepressor Activity RNA Binding Protein Binding Zinc Ion Binding Identical Protein Binding Pre-mRNA Branch Point Binding
	Biological Process	Spliceosomal SnRNP Assembly Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Cell Proliferation Secretory Columnal Luminar Epithelial Cell Differentiation Involved In Prostate Glandular Acinus Development Negative Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development Positive Regulation Of Nucleic Acid-templated Transcription	Spliceosomal Complex Assembly MRNA 3'-splice Site Recognition MRNA Splicing, Via Spliceosome Male Sex Determination Nuclear Body Organization Leydig Cell Differentiation Negative Regulation Of Smooth Muscle Cell Proliferation Regulation Of Steroid Biosynthetic Process Negative Regulation Of Nucleic Acid-templated Transcription
Pathways		snRNP Assembly RMTs methylate histone arginines	mRNA Splicing - Major Pathway
Drugs			Artenimol
Diseases
GWAS			Urate levels ( 21768215)
Interacting Genes		44 interacting genes: AQR BAG2 CDK19 CDK8 CLNS1A CREBBP CTDP1 GLI1 GPKOW H2AC21 HNRNPM LSM3 NKX3-1 PCBP2 PITRM1 PPIL1 PPP1R8 PQBP1 PRKG1 PRKG2 PRMT5 QKI RBM5 RIOK1 SAP30BP SF1 SF3A1 SF3B4 SIRT7 SMAD1 SMYD1 SNRPB SNRPC SNRPD1 SNRPD2 SNRPD3 SNRPE SNRPF SUZ12 THOC1 TOE1 YWHAB YWHAQ ZNF207	43 interacting genes: APBB1 ATXN1 BCAS2 BCL2 CIAO1 DDX17 EWSR1 FAM168A FUS GAS7 HNRNPF HNRNPH1 HNRNPH2 HNRNPK HNRNPUL1 IL7R ILF3 ITCH KRTAP26-1 MKRN3 NFKB1 PLSCR1 PRKG1 PRPF40A PSMA3 RBM10 RBM17 RBM4 RBM7 RBPMS SF3A1 SF3B1 SF3B4 TAF15 TCERG1 TRIM23 TRIM69 U2AF2 WBP4 WDR77 WDR83 WWP2 ZNF461
Entrez ID		79084	7536
HPRD ID		14387	03306
Ensembl ID		ENSG00000116455	ENSG00000168066
Uniprot IDs		A0A024R0H7 Q9BQA1	A0A024R566 A0A024R572 A0A024R588 A0A024R5D9 B4DX42 Q15637
PDB IDs		4GQB 4X60 4X61 4X63 5C9Z 5EMJ 5EMK 5EML 5EMM 5FA5 6CKC 6K1S	1K1G 1O0P 1OPI 2M09 2M0G 4FXW 4FXX
Enriched GO Terms of Interacting Partners?
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