SF1 and RBM10

Number of citations of the paper that reports this interaction (PubMedID 22365833)
132

Data Source:
BioGRID (two hybrid, two hybrid)

		SF1	RBM10
Description		splicing factor 1	RNA binding motif protein 10
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex Ribosome Nuclear Body	Nucleus Nuclear Speck Protein-containing Complex
	Molecular Function	Transcription Corepressor Activity RNA Binding Protein Binding Zinc Ion Binding Identical Protein Binding Pre-mRNA Branch Point Binding	RNA Binding Protein Binding MiRNA Binding Identical Protein Binding Metal Ion Binding
	Biological Process	Spliceosomal Complex Assembly MRNA 3'-splice Site Recognition MRNA Splicing, Via Spliceosome Male Sex Determination Nuclear Body Organization Leydig Cell Differentiation Negative Regulation Of Smooth Muscle Cell Proliferation Regulation Of Steroid Biosynthetic Process Negative Regulation Of Nucleic Acid-templated Transcription	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Processing Biological_process Negative Regulation Of Cell Proliferation RNA Splicing Positive Regulation Of Smooth Muscle Cell Apoptotic Process Negative Regulation Of MRNA Splicing, Via Spliceosome 3'-UTR-mediated MRNA Stabilization
Pathways		mRNA Splicing - Major Pathway
Drugs		Artenimol
Diseases			TARP syndrome
GWAS		Urate levels ( 21768215)
Interacting Genes		43 interacting genes: APBB1 ATXN1 BCAS2 BCL2 CIAO1 DDX17 EWSR1 FAM168A FUS GAS7 HNRNPF HNRNPH1 HNRNPH2 HNRNPK HNRNPUL1 IL7R ILF3 ITCH KRTAP26-1 MKRN3 NFKB1 PLSCR1 PRKG1 PRPF40A PSMA3 RBM10 RBM17 RBM4 RBM7 RBPMS SF3A1 SF3B1 SF3B4 TAF15 TCERG1 TRIM23 TRIM69 U2AF2 WBP4 WDR77 WDR83 WWP2 ZNF461	49 interacting genes: AKAP9 ATE1 ATN1 CASK CBLL1 CCAR1 CEP70 CPSF7 CSNK2A1 DDX17 DDX5 FAM124A GTSE1 HNRNPH2 HNRNPK HNRNPLL IK KHDRBS2 MAPRE2 MEOX2 NDEL1 NIN PCBP1 PRC1 PRCC PRDM14 PRR20A PTBP1 PTBP2 RBM12B RBM14 RBM4 RBMY1F SF1 SF3A1 SF3B2 SF3B4 SLAIN1 SNU13 SREK1 SRSF6 TBC1D22B THAP1 TLE5 U2AF1 UBQLN4 ZBTB24 ZFP64 ZNF473
Entrez ID		7536	8241
HPRD ID		03306	02095
Ensembl ID		ENSG00000168066	ENSG00000182872
Uniprot IDs		A0A024R566 A0A024R572 A0A024R588 A0A024R5D9 B4DX42 Q15637	A0A0S2Z4W4 A0A0S2Z4X1 P98175 Q7Z3D7
PDB IDs		1K1G 1O0P 1OPI 2M09 2M0G 4FXW 4FXX	2LXI 2M2B 2MXV 2MXW 5ZSW 5ZSY
Enriched GO Terms of Interacting Partners?
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