SF1 and CIAO1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid, affinity chromatography technology)

		SF1	CIAO1
Description		splicing factor 1	cytosolic iron-sulfur assembly component 1
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex Ribosome Nuclear Body	Cytoplasm MMXD Complex CIA Complex
	Molecular Function	Transcription Corepressor Activity RNA Binding Protein Binding Zinc Ion Binding Identical Protein Binding Pre-mRNA Branch Point Binding	Protein Binding
	Biological Process	Spliceosomal Complex Assembly MRNA 3'-splice Site Recognition MRNA Splicing, Via Spliceosome Male Sex Determination Nuclear Body Organization Leydig Cell Differentiation Negative Regulation Of Smooth Muscle Cell Proliferation Regulation Of Steroid Biosynthetic Process Negative Regulation Of Nucleic Acid-templated Transcription	Regulation Of Transcription By RNA Polymerase II Chromosome Segregation Positive Regulation Of Cell Proliferation Iron-sulfur Cluster Assembly Protein Maturation By Iron-sulfur Cluster Transfer
Pathways		mRNA Splicing - Major Pathway	Cytosolic iron-sulfur cluster assembly
Drugs		Artenimol
Diseases
GWAS		Urate levels ( 21768215)
Interacting Genes		43 interacting genes: APBB1 ATXN1 BCAS2 BCL2 CIAO1 DDX17 EWSR1 FAM168A FUS GAS7 HNRNPF HNRNPH1 HNRNPH2 HNRNPK HNRNPUL1 IL7R ILF3 ITCH KRTAP26-1 MKRN3 NFKB1 PLSCR1 PRKG1 PRPF40A PSMA3 RBM10 RBM17 RBM4 RBM7 RBPMS SF3A1 SF3B1 SF3B4 TAF15 TCERG1 TRIM23 TRIM69 U2AF2 WBP4 WDR77 WDR83 WWP2 ZNF461	9 interacting genes: APP CCDC7 CIAO2A CIAO2B GOLM1 MEOX1 SF1 SRPK1 WT1
Entrez ID		7536	9391
HPRD ID		03306	16057
Ensembl ID		ENSG00000168066	ENSG00000144021
Uniprot IDs		A0A024R566 A0A024R572 A0A024R588 A0A024R5D9 B4DX42 Q15637	O76071
PDB IDs		1K1G 1O0P 1OPI 2M09 2M0G 4FXW 4FXX	3FM0
Enriched GO Terms of Interacting Partners?
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