REEP5 and LGR5

		REEP5	LGR5
Description		receptor accessory protein 5	leucine rich repeat containing G protein-coupled receptor 5
Image		No pdb structure
GO Annotations	Cellular Component	Integral Component Of Membrane Endoplasmic Reticulum Tubular Network	Plasma Membrane Integral Component Of Plasma Membrane Trans-Golgi Network Membrane
	Molecular Function	Molecular_function Protein Binding	Transmembrane Signaling Receptor Activity G Protein-coupled Receptor Activity Protein Binding G Protein-coupled Peptide Receptor Activity Protein-hormone Receptor Activity
	Biological Process	Biological_process	Hair Follicle Development G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Activation Of Adenylate Cyclase Activity Hormone-mediated Signaling Pathway Oocyte Differentiation Regulation Of Cell Proliferation Inner Ear Development Positive Regulation Of Canonical Wnt Signaling Pathway Epithelial Cell Proliferation Involved In Renal Tubule Morphogenesis
Pathways		Olfactory Signaling Pathway	Regulation of FZD by ubiquitination
Drugs
Diseases
GWAS		Attention deficit hyperactivity disorder ( 18839057) Reaction time ( 29844566)	Asthma (adult onset) ( 31036433) Asthma (childhood onset) ( 31036433) Type 2 diabetes ( 22885922 18372903 29358691 30297969 20581827)
Interacting Genes		16 interacting genes: ARFGAP1 CD14 CPOX EDC3 GPX3 GTF2H1 HBEGF LGR5 NUDT3 PDK4 PDLIM3 RAB5B RABAC1 RGS2 TENT4A VKORC1	2 interacting genes: REEP5 RSPO2
Entrez ID		7905	8549
HPRD ID		15918	05979
Ensembl ID		ENSG00000129625	ENSG00000139292
Uniprot IDs		Q00765	A0A0A8K8C7 O75473
PDB IDs			4BSR 4BSS 4BST 4BSU 4KNG 4UFR 4UFS
Enriched GO Terms of Interacting Partners?
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