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REEP5 and CD14
REEP5
CD14
Description
receptor accessory protein 5
CD14 molecule
Image
No pdb structure
GO Annotations
Cellular Component
Integral Component Of Membrane
Endoplasmic Reticulum Tubular Network
Extracellular Region
Extracellular Space
Golgi Apparatus
Plasma Membrane
External Side Of Plasma Membrane
Cell Surface
Endosome Membrane
Secretory Granule Membrane
Anchored Component Of External Side Of Plasma Membrane
Membrane Raft
Lipopolysaccharide Receptor Complex
Extracellular Exosome
Molecular Function
Molecular_function
Protein Binding
Lipopolysaccharide Binding
Opsonin Receptor Activity
Protein Binding
Peptidoglycan Receptor Activity
Lipoteichoic Acid Binding
Lipopeptide Binding
Biological Process
Biological_process
Toll-like Receptor Signaling Pathway
MyD88-dependent Toll-like Receptor Signaling Pathway
MyD88-independent Toll-like Receptor Signaling Pathway
Receptor-mediated Endocytosis
Phagocytosis
Apoptotic Process
Inflammatory Response
Cell Surface Receptor Signaling Pathway
I-kappaB Kinase/NF-kappaB Signaling
Response To Heat
Lipopolysaccharide-mediated Signaling Pathway
Response To Magnesium Ion
Positive Regulation Of Type I Interferon Production
Positive Regulation Of Interferon-gamma Production
Positive Regulation Of Tumor Necrosis Factor Production
Negative Regulation Of MyD88-independent Toll-like Receptor Signaling Pathway
Toll-like Receptor 4 Signaling Pathway
Response To Tumor Necrosis Factor
TRIF-dependent Toll-like Receptor Signaling Pathway
Toll-like Receptor TLR1:TLR2 Signaling Pathway
Toll-like Receptor TLR6:TLR2 Signaling Pathway
Neutrophil Degranulation
Innate Immune Response
Response To Ethanol
Positive Regulation Of Endocytosis
Positive Regulation Of Cytokine Secretion
Response To Electrical Stimulus
Necroptotic Process
Cellular Response To Molecule Of Bacterial Origin
Cellular Response To Lipopolysaccharide
Cellular Response To Lipoteichoic Acid
Cellular Response To Diacyl Bacterial Lipopeptide
Cellular Response To Triacyl Bacterial Lipopeptide
Apoptotic Signaling Pathway
Positive Regulation Of NIK/NF-kappaB Signaling
Positive Regulation Of Interleukin-8 Secretion
Pathways
Olfactory Signaling Pathway
ER-Phagosome pathway
Caspase activation via Death Receptors in the presence of ligand
Toll Like Receptor 4 (TLR4) Cascade
Transfer of LPS from LBP carrier to CD14
MyD88:MAL(TIRAP) cascade initiated on plasma membrane
MyD88-independent TLR4 cascade
Toll Like Receptor TLR1:TLR2 Cascade
Toll Like Receptor TLR6:TLR2 Cascade
TRIF-mediated programmed cell death
MyD88 deficiency (TLR2/4)
IRAK4 deficiency (TLR2/4)
Regulation of TLR by endogenous ligand
Neutrophil degranulation
Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
IKK complex recruitment mediated by RIP1
TRAF6-mediated induction of TAK1 complex within TLR4 complex
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
Drugs
Diseases
Asthma
GWAS
Attention deficit hyperactivity disorder (
18839057
)
Reaction time (
29844566
)
Blood protein levels (
30072576
)
Schizophrenia (
29483656
)
Interacting Genes
16 interacting genes:
ARFGAP1
CD14
CPOX
EDC3
GPX3
GTF2H1
HBEGF
LGR5
NUDT3
PDK4
PDLIM3
RAB5B
RABAC1
RGS2
TENT4A
VKORC1
15 interacting genes:
ARFGAP3
CD55
GJB2
IRAK3
ITGB2
LBP
LGALS3BP
LTF
POLR2J
PPP3R2
REEP5
TLR2
TLR3
TLR4
TNFRSF1B
Entrez ID
7905
929
HPRD ID
15918
01151
Ensembl ID
ENSG00000129625
ENSG00000170458
Uniprot IDs
Q00765
P08571
PDB IDs
4GLP
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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