REEP5 and RAB5B

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		REEP5	RAB5B
Description		receptor accessory protein 5	RAB5B, member RAS oncogene family
Image		No pdb structure
GO Annotations	Cellular Component	Integral Component Of Membrane Endoplasmic Reticulum Tubular Network	Intracellular Endosome Early Endosome Plasma Membrane Endomembrane System Membrane Endocytic Vesicle Secretory Granule Membrane Early Endosome Membrane Melanosome Intracellular Membrane-bounded Organelle Extracellular Exosome Anchored Component Of Synaptic Vesicle Membrane
	Molecular Function	Molecular_function Protein Binding	GTPase Activity Protein Binding GTP Binding GDP Binding GTP-dependent Protein Binding
	Biological Process	Biological_process	Intracellular Protein Transport Endocytosis Endosome Organization Antigen Processing And Presentation Regulation Of Endocytosis Rab Protein Signal Transduction Neutrophil Degranulation Plasma Membrane To Endosome Transport
Pathways		Olfactory Signaling Pathway	Neutrophil degranulation TBC/RABGAPs Clathrin-mediated endocytosis RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases
GWAS		Attention deficit hyperactivity disorder ( 18839057) Reaction time ( 29844566)	Allergic disease (asthma, hay fever or eczema) ( 29785011) Anorexia nervosa ( 28494655) Asthma ( 30929738 31619474) Asthma (adult onset) ( 31036433) Asthma (childhood onset) ( 31036433 30929738) Asthma or allergic disease (pleiotropy) ( 29785011) Cognitive function ( 25644384) FEV1 ( 30804560) Gastroesophageal reflux disease ( 31527586) Lung function (FEV1) ( 30061609) Lung function (FEV1/FVC) ( 30804560) Medication use (drugs for peptic ulcer and gastro-oesophageal reflux disease) ( 31015401) Polycystic ovary syndrome ( 22885925 30566500) Sum eosinophil basophil counts ( 27863252) Type 1 diabetes ( 18198356) Vitiligo ( 22951725)
Interacting Genes		16 interacting genes: ARFGAP1 CD14 CPOX EDC3 GPX3 GTF2H1 HBEGF LGR5 NUDT3 PDK4 PDLIM3 RAB5B RABAC1 RGS2 TENT4A VKORC1	17 interacting genes: APOA5 CDK1 CHM EEA1 GLP1R PIK3CB PRIM1 RABAC1 REEP5 RIN1 RIN2 RIN3 SGSM3 SUN2 TBC1D15 TBC1D17 TFRC
Entrez ID		7905	5869
HPRD ID		15918	01544
Ensembl ID		ENSG00000129625	ENSG00000111540
Uniprot IDs		Q00765	A0A024RB09 P61020
PDB IDs			2HEI
Enriched GO Terms of Interacting Partners?
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