ZBTB25 and SORBS3

Number of citations of the paper that reports this interaction (PubMedID 16189514)
1016

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		ZBTB25	SORBS3
Description		zinc finger and BTB domain containing 25	sorbin and SH3 domain containing 3
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm	Nucleus Cytosol Cytoskeleton Focal Adhesion
	Molecular Function	DNA Binding DNA-binding Transcription Factor Activity Protein Binding Metal Ion Binding	Structural Constituent Of Cytoskeleton Protein Binding Transcription Factor Binding Vinculin Binding
	Biological Process	Regulation Of Transcription, DNA-templated Gene Expression	Negative Regulation Of Transcription By RNA Polymerase II Muscle Contraction Actin Filament Organization Cell Adhesion Cell-substrate Adhesion Positive Regulation Of MAPK Cascade Positive Regulation Of Cytoskeleton Organization Positive Regulation Of Stress Fiber Assembly
Pathways			Smooth Muscle Contraction
Drugs
Diseases
GWAS		Heel bone mineral density ( 30598549) Lymphocyte counts ( 27863252) Lymphocyte percentage of white cells ( 27863252)	Diastolic blood pressure ( 30224653) HIV-1 viral setpoint ( 20205591) Itch intensity from mosquito bite adjusted by bite size ( 28199695) Parkinson's disease ( 28892059)
Interacting Genes		22 interacting genes: APIP COIL CYP2J2 DDIT3 FCGR3A FHL2 HCLS1 KCTD1 KXD1 LZTS2 MAPK9 MDFI PCBD1 PNMA5 SEPHS1 SORBS3 SSX3 SUMO2 TNIP1 TRAF2 TSSK3 ZBTB1	46 interacting genes: ABL1 ADAM15 ADAMTSL4 ARNT2 CBLB CPEB2 CPNE2 CPSF7 DDX17 DIP2A DLG5 DMRTB1 DVL2 EFS EIF3H FASLG FLOT1 HNRNPK HNRNPUL1 INPPL1 KIAA0408 KIAA1217 MAPK1 MAPK3 NCK1 NCKIPSD NOTCH3 PAK2 PAK5 RBMX SAFB2 SAXO1 SH2D4A SOCS7 SRCIN1 TBC1D22B TRIM23 TRIM27 TRIM41 VARS2 VPS37B VPS37C ZBED1 ZBTB25 ZBTB7B ZC4H2
Entrez ID		7597	10174
HPRD ID		01926	11535
Ensembl ID		ENSG00000089775	ENSG00000120896
Uniprot IDs		G3V2K3 P24278	O60504
PDB IDs			2CT3 2DLM 2NWM 2YUP
Enriched GO Terms of Interacting Partners?
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