SORBS3 and SOCS7

Number of citations of the paper that reports this interaction (PubMedID 15242778)
9

Data Source:
HPRD (two hybrid, in vivo)

		SORBS3	SOCS7
Description		sorbin and SH3 domain containing 3	suppressor of cytokine signaling 7
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol Cytoskeleton Focal Adhesion	Nucleus Cytosol Plasma Membrane Phosphatidylinositol 3-kinase Complex
	Molecular Function	Structural Constituent Of Cytoskeleton Protein Binding Transcription Factor Binding Vinculin Binding	Protein Binding SH3 Domain Binding 1-phosphatidylinositol-3-kinase Regulator Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Muscle Contraction Actin Filament Organization Cell Adhesion Cell-substrate Adhesion Positive Regulation Of MAPK Cascade Positive Regulation Of Cytoskeleton Organization Positive Regulation Of Stress Fiber Assembly	Biological_process Negative Regulation Of Signal Transduction Protein Ubiquitination Intracellular Signal Transduction Regulation Of Growth Regulation Of Phosphatidylinositol 3-kinase Activity Phosphatidylinositol Phosphorylation
Pathways		Smooth Muscle Contraction
Drugs
Diseases
GWAS		Diastolic blood pressure ( 30224653) HIV-1 viral setpoint ( 20205591) Itch intensity from mosquito bite adjusted by bite size ( 28199695) Parkinson's disease ( 28892059)	Ovarian cancer ( 23535730)
Interacting Genes		46 interacting genes: ABL1 ADAM15 ADAMTSL4 ARNT2 CBLB CPEB2 CPNE2 CPSF7 DDX17 DIP2A DLG5 DMRTB1 DVL2 EFS EIF3H FASLG FLOT1 HNRNPK HNRNPUL1 INPPL1 KIAA0408 KIAA1217 MAPK1 MAPK3 NCK1 NCKIPSD NOTCH3 PAK2 PAK5 RBMX SAFB2 SAXO1 SH2D4A SOCS7 SRCIN1 TBC1D22B TRIM23 TRIM27 TRIM41 VARS2 VPS37B VPS37C ZBED1 ZBTB25 ZBTB7B ZC4H2	12 interacting genes: DAB1 EGFR GRB2 IRS2 IRS4 NCK1 PIK3R1 PIK3R2 PLCG1 SORBS3 TUBA1A TUBB4B
Entrez ID		10174	30837
HPRD ID		11535	12299
Ensembl ID		ENSG00000120896	ENSG00000274211
Uniprot IDs		O60504	O14512
PDB IDs		2CT3 2DLM 2NWM 2YUP
Enriched GO Terms of Interacting Partners?
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