SORBS3 and ZC4H2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		SORBS3	ZC4H2
Description		sorbin and SH3 domain containing 3	zinc finger C4H2-type containing
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol Cytoskeleton Focal Adhesion	Nucleus Cytoplasm Cell Junction Postsynaptic Membrane
	Molecular Function	Structural Constituent Of Cytoskeleton Protein Binding Transcription Factor Binding Vinculin Binding	Protein Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Muscle Contraction Actin Filament Organization Cell Adhesion Cell-substrate Adhesion Positive Regulation Of MAPK Cascade Positive Regulation Of Cytoskeleton Organization Positive Regulation Of Stress Fiber Assembly	Nervous System Development Neuromuscular Junction Development Spinal Cord Motor Neuron Differentiation Positive Regulation Of Neuron Differentiation
Pathways		Smooth Muscle Contraction
Drugs
Diseases
GWAS		Diastolic blood pressure ( 30224653) HIV-1 viral setpoint ( 20205591) Itch intensity from mosquito bite adjusted by bite size ( 28199695) Parkinson's disease ( 28892059)	Male-pattern baldness ( 28196072)
Interacting Genes		46 interacting genes: ABL1 ADAM15 ADAMTSL4 ARNT2 CBLB CPEB2 CPNE2 CPSF7 DDX17 DIP2A DLG5 DMRTB1 DVL2 EFS EIF3H FASLG FLOT1 HNRNPK HNRNPUL1 INPPL1 KIAA0408 KIAA1217 MAPK1 MAPK3 NCK1 NCKIPSD NOTCH3 PAK2 PAK5 RBMX SAFB2 SAXO1 SH2D4A SOCS7 SRCIN1 TBC1D22B TRIM23 TRIM27 TRIM41 VARS2 VPS37B VPS37C ZBED1 ZBTB25 ZBTB7B ZC4H2	9 interacting genes: DGCR6 KXD1 SORBS3 TRIM14 ZNF223 ZNF250 ZNF490 ZNF524 ZNF688
Entrez ID		10174	55906
HPRD ID		11535	06584
Ensembl ID		ENSG00000120896	ENSG00000126970
Uniprot IDs		O60504	Q9NQZ6
PDB IDs		2CT3 2DLM 2NWM 2YUP
Enriched GO Terms of Interacting Partners?
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