WNT2 and RRAGC

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		WNT2	RRAGC
Description		Wnt family member 2	Ras related GTP binding C
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Cytoplasm Extrinsic Component Of External Side Of Plasma Membrane Collagen-containing Extracellular Matrix Wnt Signalosome	Nucleus Nucleoplasm Cytoplasm Lysosome Cytosol EGO Complex Intracellular Membrane-bounded Organelle Gtr1-Gtr2 GTPase Complex
	Molecular Function	Frizzled Binding Cytokine Activity Protein Binding Receptor Ligand Activity	Magnesium Ion Binding GTPase Activity Protein Binding GTP Binding GDP Binding Protein Heterodimerization Activity GTPase Binding
	Biological Process	Positive Regulation Of Endothelial Cell Proliferation Positive Regulation Of Mesenchymal Cell Proliferation Lens Development In Camera-type Eye Cell-cell Signaling Positive Regulation Of Cell Proliferation Wnt Signaling Pathway Neurogenesis Neuron Differentiation Lung Development Cell Proliferation In Midbrain Cell Fate Commitment Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Fibroblast Proliferation Positive Regulation Of Neurogenesis Positive Regulation Of DNA-binding Transcription Factor Activity Atrial Cardiac Muscle Tissue Morphogenesis Positive Regulation Of Cardiac Muscle Cell Proliferation Canonical Wnt Signaling Pathway Cardiac Epithelial To Mesenchymal Transition Lung Induction Positive Regulation Of Epithelial Cell Proliferation Involved In Lung Morphogenesis Labyrinthine Layer Blood Vessel Development Iris Morphogenesis Mammary Gland Epithelium Development Cellular Response To Retinoic Acid Cellular Response To Transforming Growth Factor Beta Stimulus Midbrain Dopaminergic Neuron Differentiation Canonical Wnt Signaling Pathway Involved In Midbrain Dopaminergic Neuron Differentiation	Transcription, DNA-templated Apoptotic Process Cell Cycle Arrest Small GTPase Mediated Signal Transduction RNA Splicing Cellular Response To Starvation Regulation Of Autophagy Regulation Of Macroautophagy Regulation Of TOR Signaling Positive Regulation Of TOR Signaling Cellular Response To Amino Acid Starvation Cellular Protein Localization Response To Amino Acid Cellular Response To Amino Acid Stimulus Regulation Of TORC1 Signaling
Pathways		WNT ligand biogenesis and trafficking WNT ligand biogenesis and trafficking Class B/2 (Secretin family receptors)	Macroautophagy mTOR signalling mTORC1-mediated signalling Energy dependent regulation of mTOR by LKB1-AMPK TP53 Regulates Metabolic Genes Regulation of PTEN gene transcription Amino acids regulate mTORC1
Drugs
Diseases
GWAS		Dupuytren's disease ( 28886342 21732829) Inflammatory bowel disease ( 28067908) Response to platinum-based chemotherapy in non-small-cell lung cancer ( 22872573) Tonsillectomy ( 27182965 28928442) Ulcerative colitis ( 28067908) Uterine fibroids ( 31649266)	Beard thickness ( 26926045) Blood protein levels ( 28240269)
Interacting Genes		8 interacting genes: AQP5 FZD1 FZD9 HCK RRAGC SFRP1 UQCR11 WNT3A	7 interacting genes: ATXN1L DEPDC5 MPP3 NOL8 RRAGA RRAGB WNT2
Entrez ID		7472	64121
HPRD ID		00999	12198
Ensembl ID		ENSG00000105989	ENSG00000116954
Uniprot IDs		A0A384MDX3 P09544	B4DQ03 B4DQG4 Q9HB90
PDB IDs			3LLU 6CES 6EHR 6NZD 6S6A 6S6D 6SB0 6SB2 6U62 6ULG
Enriched GO Terms of Interacting Partners?
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