UCP1 and TOMM20

Number of citations of the paper that reports this interaction (PubMedID 9119086)
8

Data Source:
HPRD (in vitro)

		UCP1	TOMM20
Description		uncoupling protein 1	translocase of outer mitochondrial membrane 20
Image		No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Integral Component Of Membrane	Mitochondrion Mitochondrial Outer Membrane Mitochondrial Outer Membrane Translocase Complex Integral Component Of Mitochondrial Outer Membrane Mitochondria-associated ER Membrane
	Molecular Function	Oxidative Phosphorylation Uncoupler Activity Transmembrane Transporter Activity Purine Ribonucleotide Binding Long-chain Fatty Acid Binding Cardiolipin Binding	Protein Binding P-P-bond-hydrolysis-driven Protein Transmembrane Transporter Activity Mitochondrion Targeting Sequence Binding Unfolded Protein Binding
	Biological Process	Diet Induced Thermogenesis Regulation Of Transcription By RNA Polymerase II Response To Temperature Stimulus Response To Cold Response To Nutrient Levels Cellular Response To Hormone Stimulus Cellular Response To Reactive Oxygen Species Brown Fat Cell Differentiation Cellular Response To Cold Cellular Response To Fatty Acid Positive Regulation Of Cold-induced Thermogenesis Proton Transmembrane Transport Regulation Of Reactive Oxygen Species Biosynthetic Process Mitochondrial Transmembrane Transport Adaptive Thermogenesis	Protein Targeting To Mitochondrion Response To Muscle Activity TRNA Import Into Mitochondrion Macroautophagy Protein Deubiquitination Protein Import Into Mitochondrial Matrix Mitochondrial Outer Membrane Translocase Complex Assembly Response To 3,3',5-triiodo-L-thyronine
Pathways		The fatty acid cycling model The proton buffering model	Mitochondrial protein import Pink/Parkin Mediated Mitophagy Ub-specific processing proteases
Drugs
Diseases
GWAS			Cholesterol, total ( 20686565) Cobalt levels ( 26025379) Immune reponse to smallpox (secreted IL-2) ( 22610502) LDL cholesterol ( 20686565) Night sleep phenotypes ( 27126917) Obesity-related traits ( 23251661)
Interacting Genes		2 interacting genes: CIDEA TOMM20	19 interacting genes: AIP APOA1 ATXN1 BAG6 BCL2 CDC73 CEP126 DHFR FBXO7 FEZ1 HAP1 HSD17B10 OTC PPHLN1 PTN TOMM22 TOMM40 UCP1 VDAC1
Entrez ID		7350	9804
HPRD ID		00221	03507
Ensembl ID		ENSG00000109424	ENSG00000173726
Uniprot IDs		P25874 Q4KMT7	A0A024R3W2 Q15388
PDB IDs			4APO
Enriched GO Terms of Interacting Partners?
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