THRSP and RB1CC1

Number of citations of the paper that reports this interaction (PubMedID 25640309)
5

Data Source:
BioGRID (two hybrid)

		THRSP	RB1CC1
Description		thyroid hormone responsive	RB1 inducible coiled-coil 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytosol	Phagophore Assembly Site Lysosome Endoplasmic Reticulum Membrane Cytosol Extrinsic Component Of Membrane Nuclear Membrane Phagophore Assembly Site Membrane Atg1/ULK1 Kinase Complex
	Molecular Function	Identical Protein Binding Protein Homodimerization Activity	Protein Binding Protein Kinase Binding Molecular Adaptor Activity
	Biological Process	Lipid Metabolic Process Carnitine Shuttle Response To Bacterium Regulation Of Triglyceride Biosynthetic Process Regulation Of Lipid Biosynthetic Process	Autophagosome Assembly Autophagy Of Mitochondrion Liver Development Positive Regulation Of Protein Phosphorylation Autophagy Cell Cycle Heart Development Macroautophagy Regulation Of Macroautophagy Autophagy Of Peroxisome Piecemeal Microautophagy Of The Nucleus Positive Regulation Of Cell Size Positive Regulation Of JNK Cascade Reticulophagy Glycophagy Negative Regulation Of Extrinsic Apoptotic Signaling Pathway
Pathways		Carnitine metabolism	Macroautophagy
Drugs
Diseases
GWAS		Menarche (age at onset) ( 25231870) Tourette syndrome ( 30818990)	Immunoglobulin light chain (AL) amyloidosis (liver involvement) ( 28679651) Mitochondrial DNA copy number (white blood cells) ( 30704525) Waist circumference adjusted for body mass index ( 28552196)
Interacting Genes		22 interacting genes: AKT1 AURKA BAG4 BCAR3 BRMS1 ERBB2 FGFR4 FZR1 HMMR IGF1R KRAS LSP1 PALB2 PARP1 PIK3CA PTPN1 RB1CC1 SMAD4 STK11 TGFB1 TSG101 WT1	36 interacting genes: ATG13 BAP1 BLID CALCOCO2 COP1 EPSTI1 ERRFI1 EXOC1 GABARAP GABARAPL1 GABARAPL2 GLCE GREB1 HBP1 IL13RA2 IL24 ITIH5 LYPD3 MADD MAP1LC3A MAP1LC3B MAP1LC3C MRC2 NSD3 PSMC3IP PTK2 PTK2B RNF20 SYN1 TBKBP1 THRSP UBC UMPS VHL VPS45 WIF1
Entrez ID		7069	9821
HPRD ID		03566	06019
Ensembl ID		ENSG00000151365	ENSG00000023287
Uniprot IDs		Q92748	Q8TDY2
PDB IDs			6DCE 6GMA
Enriched GO Terms of Interacting Partners?
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