THRSP and BAG4

Number of citations of the paper that reports this interaction (PubMedID 25640309)
5

Data Source:
BioGRID (two hybrid)

		THRSP	BAG4
Description		thyroid hormone responsive	BAG cochaperone 4
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytosol	Nucleus Cytosol Plasma Membrane
	Molecular Function	Identical Protein Binding Protein Homodimerization Activity	RNA Binding Protein Binding Ubiquitin Protein Ligase Binding Chaperone Binding
	Biological Process	Lipid Metabolic Process Carnitine Shuttle Response To Bacterium Regulation Of Triglyceride Biosynthetic Process Regulation Of Lipid Biosynthetic Process	Protein Folding Positive Regulation Of Fibroblast Migration Positive Regulation Of Actin Filament Polymerization Positive Regulation Of Peptidyl-serine Phosphorylation Tumor Necrosis Factor-mediated Signaling Pathway Negative Regulation Of Apoptotic Process Positive Regulation Of Cell Adhesion Positive Regulation Of Stress Fiber Assembly Positive Regulation Of Protein Kinase B Signaling Cellular Response To Tumor Necrosis Factor Cellular Response To Epidermal Growth Factor Stimulus Protein Localization To Plasma Membrane Ruffle Assembly Regulation Of Cellular Response To Heat Negative Regulation Of Protein Targeting To Mitochondrion Negative Regulation Of Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase Activity
Pathways		Carnitine metabolism	Regulation of HSF1-mediated heat shock response Signaling by FGFR1 in disease TNF signaling Signaling by plasma membrane FGFR1 fusions
Drugs
Diseases
GWAS		Menarche (age at onset) ( 25231870) Tourette syndrome ( 30818990)	Autism spectrum disorder or schizophrenia ( 28540026) Schizophrenia ( 28991256 29483656)
Interacting Genes		22 interacting genes: AKT1 AURKA BAG4 BCAR3 BRMS1 ERBB2 FGFR4 FZR1 HMMR IGF1R KRAS LSP1 PALB2 PARP1 PIK3CA PTPN1 RB1CC1 SMAD4 STK11 TGFB1 TSG101 WT1	38 interacting genes: APOBEC1 ATAD2 BAP1 BCAS3 BCL2 BEX1 CASZ1 CCL5 DIRAS3 EPSTI1 ERRFI1 GLCE GRAP2 HSPA1A HSPA8 IL13RA2 IL24 ITIH5 KLK5 KLK7 KLK9 LRATD2 LYPD3 MRC2 MTA3 NAT2 PDLIM2 PLAT PRDM14 RASL10B RHOBTB2 RNF20 RPL22 SCGB3A1 TBC1D7 THRSP TNFRSF1A TNFRSF25
Entrez ID		7069	9530
HPRD ID		03566	04861
Ensembl ID		ENSG00000151365	ENSG00000156735
Uniprot IDs		Q92748	O95429
PDB IDs			1M62 1M7K
Enriched GO Terms of Interacting Partners?
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