RB1CC1 and TBKBP1

Number of citations of the paper that reports this interaction (PubMedID 21903422)
114

Data Source:
BioGRID (affinity chromatography technology, pull down)

		RB1CC1	TBKBP1
Description		RB1 inducible coiled-coil 1	TBK1 binding protein 1
Image			No pdb structure
GO Annotations	Cellular Component	Phagophore Assembly Site Lysosome Endoplasmic Reticulum Membrane Cytosol Extrinsic Component Of Membrane Nuclear Membrane Phagophore Assembly Site Membrane Atg1/ULK1 Kinase Complex
	Molecular Function	Protein Binding Protein Kinase Binding Molecular Adaptor Activity	Protein Binding Metal Ion Binding
	Biological Process	Autophagosome Assembly Autophagy Of Mitochondrion Liver Development Positive Regulation Of Protein Phosphorylation Autophagy Cell Cycle Heart Development Macroautophagy Regulation Of Macroautophagy Autophagy Of Peroxisome Piecemeal Microautophagy Of The Nucleus Positive Regulation Of Cell Size Positive Regulation Of JNK Cascade Reticulophagy Glycophagy Negative Regulation Of Extrinsic Apoptotic Signaling Pathway	Viral Process Innate Immune Response
Pathways		Macroautophagy
Drugs
Diseases
GWAS		Immunoglobulin light chain (AL) amyloidosis (liver involvement) ( 28679651) Mitochondrial DNA copy number (white blood cells) ( 30704525) Waist circumference adjusted for body mass index ( 28552196)	Ankylosing spondylitis ( 23749187 21743469) Asthma ( 31619474) Asthma (childhood onset) ( 31036433) Body mass index ( 26426971 28448500) Body mass index (joint analysis main effects and physical activity interaction) ( 28448500) Body mass index in physically inactive individuals ( 28448500) Multiple sclerosis ( 22190364) Very long-chain saturated fatty acid levels (fatty acid 20:0) ( 25378659)
Interacting Genes		36 interacting genes: ATG13 BAP1 BLID CALCOCO2 COP1 EPSTI1 ERRFI1 EXOC1 GABARAP GABARAPL1 GABARAPL2 GLCE GREB1 HBP1 IL13RA2 IL24 ITIH5 LYPD3 MADD MAP1LC3A MAP1LC3B MAP1LC3C MRC2 NSD3 PSMC3IP PTK2 PTK2B RNF20 SYN1 TBKBP1 THRSP UBC UMPS VHL VPS45 WIF1	5 interacting genes: AGO2 APBA3 CBX1 RB1CC1 SKAP1
Entrez ID		9821	9755
HPRD ID		06019	12239
Ensembl ID		ENSG00000023287	ENSG00000198933
Uniprot IDs		Q8TDY2	A7MCY6
PDB IDs		6DCE 6GMA
Enriched GO Terms of Interacting Partners?
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