BAG4 and ITIH5

Number of citations of the paper that reports this interaction (PubMedID 25640309)
5

Data Source:
BioGRID (two hybrid)

		BAG4	ITIH5
Description		BAG cochaperone 4	inter-alpha-trypsin inhibitor heavy chain 5
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol Plasma Membrane	Collagen-containing Extracellular Matrix
	Molecular Function	RNA Binding Protein Binding Ubiquitin Protein Ligase Binding Chaperone Binding	Serine-type Endopeptidase Inhibitor Activity
	Biological Process	Protein Folding Positive Regulation Of Fibroblast Migration Positive Regulation Of Actin Filament Polymerization Positive Regulation Of Peptidyl-serine Phosphorylation Tumor Necrosis Factor-mediated Signaling Pathway Negative Regulation Of Apoptotic Process Positive Regulation Of Cell Adhesion Positive Regulation Of Stress Fiber Assembly Positive Regulation Of Protein Kinase B Signaling Cellular Response To Tumor Necrosis Factor Cellular Response To Epidermal Growth Factor Stimulus Protein Localization To Plasma Membrane Ruffle Assembly Regulation Of Cellular Response To Heat Negative Regulation Of Protein Targeting To Mitochondrion Negative Regulation Of Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase Activity	Negative Regulation Of Endopeptidase Activity Hyaluronan Metabolic Process
Pathways		Regulation of HSF1-mediated heat shock response Signaling by FGFR1 in disease TNF signaling Signaling by plasma membrane FGFR1 fusions
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Schizophrenia ( 28991256 29483656)	Blood protein levels ( 30072576 29875488) Metabolite levels ( 23823483) Planum temporale asymmetry index ( 31887566)
Interacting Genes		38 interacting genes: APOBEC1 ATAD2 BAP1 BCAS3 BCL2 BEX1 CASZ1 CCL5 DIRAS3 EPSTI1 ERRFI1 GLCE GRAP2 HSPA1A HSPA8 IL13RA2 IL24 ITIH5 KLK5 KLK7 KLK9 LRATD2 LYPD3 MRC2 MTA3 NAT2 PDLIM2 PLAT PRDM14 RASL10B RHOBTB2 RNF20 RPL22 SCGB3A1 TBC1D7 THRSP TNFRSF1A TNFRSF25	10 interacting genes: BAG4 BRCA1 CHEK2 ESR2 HMMR NOTCH2 PPM1D RAD51 RB1CC1 XRCC3
Entrez ID		9530	80760
HPRD ID		04861	13747
Ensembl ID		ENSG00000156735	ENSG00000123243
Uniprot IDs		O95429	A0A096LP62 C9J2H1 G5E9D8 Q86UX2 Q96JW9
PDB IDs		1M62 1M7K
Enriched GO Terms of Interacting Partners?
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