VPS16 and AKTIP

Number of citations of the paper that reports this interaction (PubMedID 18799622)
41

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vivo)

		VPS16	AKTIP
Description		VPS16 core subunit of CORVET and HOPS complexes	AKT interacting protein
Image			No pdb structure
GO Annotations	Cellular Component	Lysosome Lysosomal Membrane Endosome Early Endosome Late Endosome Autophagosome Clathrin-coated Vesicle Axon HOPS Complex Late Endosome Membrane Neuronal Cell Body Recycling Endosome	Cytosol Plasma Membrane HOPS Complex FHF Complex
	Molecular Function	Actin Binding Protein Binding Actin Filament Binding	Protein Binding Ubiquitin-like Protein Transferase Activity Ubiquitin Conjugating Enzyme Activity
	Biological Process	Intracellular Protein Transport Vacuole Organization Endosome To Lysosome Transport Endosomal Transport Regulation Of Vacuole Fusion, Non-autophagic Regulation Of SNARE Complex Assembly Autophagosome Maturation	Protein Polyubiquitination Positive Regulation Of Protein Phosphorylation Apoptotic Process Cellular Response To DNA Damage Stimulus Endosome Organization Lysosome Organization Endosome To Lysosome Transport Protein Transport Positive Regulation Of Protein Binding Early Endosome To Late Endosome Transport
Pathways
Drugs
Diseases
GWAS		Metabolite levels ( 23823483)	Body mass index ( 26426971) Body mass index (age>50) ( 26426971) Body mass index x sex x age interaction (4df test) ( 26426971) Depressive symptoms (SSRI exposure interaction) ( 25649181) Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) Hip circumference adjusted for BMI ( 25673412) Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858)
Interacting Genes		14 interacting genes: AKTIP FBXO7 HOOK1 HOOK2 HOOK3 MON1B RAB7A RILP STX1A STX7 UVRAG VPS11 VPS18 VPS33A	26 interacting genes: AKT1 ASS1 CEP126 CTBP2 DZIP3 EXOC7 FAM160A2 GTF3C1 HOOK1 HOOK2 HOOK3 IMMT IPO7 LMNA MARCHF5 MATR3 PDPK1 POLA2 RPA1 TRIM23 TRIM41 TWNK UTP14A VPS16 VPS18 VPS41
Entrez ID		64601	64400
HPRD ID		12259	07467
Ensembl ID		ENSG00000215305	ENSG00000166971
Uniprot IDs		Q9H269	A0A024R6S6 A0A024R6T5 Q9H8T0
PDB IDs		4BX9
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?