VPS16 and UVRAG

Number of citations of the paper that reports this interaction (PubMedID 18552835)
281

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology, imaging technique)
HPRD (in vivo)

		VPS16	UVRAG
Description		VPS16 core subunit of CORVET and HOPS complexes	UV radiation resistance associated
Image			No pdb structure
GO Annotations	Cellular Component	Lysosome Lysosomal Membrane Endosome Early Endosome Late Endosome Autophagosome Clathrin-coated Vesicle Axon HOPS Complex Late Endosome Membrane Neuronal Cell Body Recycling Endosome	Lytic Vacuole Autophagosome Membrane Chromosome, Centromeric Region Cytoplasm Lysosome Endosome Early Endosome Late Endosome Endoplasmic Reticulum Centrosome Midbody Phagocytic Vesicle DNA-dependent Protein Kinase Complex
	Molecular Function	Actin Binding Protein Binding Actin Filament Binding	SNARE Binding Protein Binding SH3 Domain Binding
	Biological Process	Intracellular Protein Transport Vacuole Organization Endosome To Lysosome Transport Endosomal Transport Regulation Of Vacuole Fusion, Non-autophagic Regulation Of SNARE Complex Assembly Autophagosome Maturation	DNA Repair Retrograde Vesicle-mediated Transport, Golgi To ER Autophagy Spindle Organization Chromosome Segregation Centrosome Cycle Regulation Of Cytokinesis Receptor Catabolic Process SNARE Complex Assembly Viral Entry Into Host Cell Maintenance Of Golgi Location Regulation Of Protein Serine/threonine Kinase Activity Multivesicular Body Sorting Pathway Autophagosome Maturation Double-strand Break Repair Via Classical Nonhomologous End Joining Positive Regulation Of Autophagosome Maturation
Pathways			Macroautophagy
Drugs
Diseases
GWAS		Metabolite levels ( 23823483)	Asthma ( 31619474) HDL cholesterol ( 30275531) Hemoglobin concentration ( 27863252)
Interacting Genes		14 interacting genes: AKTIP FBXO7 HOOK1 HOOK2 HOOK3 MON1B RAB7A RILP STX1A STX7 UVRAG VPS11 VPS18 VPS33A	8 interacting genes: CSNK1A1 MTOR OS9 VPS11 VPS16 VPS18 VPS33B ZRANB1
Entrez ID		64601	7405
HPRD ID		12259	03929
Ensembl ID		ENSG00000215305	ENSG00000198382
Uniprot IDs		Q9H269	Q9P2Y5
PDB IDs		4BX9
Enriched GO Terms of Interacting Partners?
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