VPS16 and HOOK3

Number of citations of the paper that reports this interaction (PubMedID 18799622)
41

Data Source:
HPRD (in vivo)

		VPS16	HOOK3
Description		VPS16 core subunit of CORVET and HOPS complexes	hook microtubule tethering protein 3
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GO Annotations	Cellular Component	Lysosome Lysosomal Membrane Endosome Early Endosome Late Endosome Autophagosome Clathrin-coated Vesicle Axon HOPS Complex Late Endosome Membrane Neuronal Cell Body Recycling Endosome	Pericentriolar Material Cytoplasm Cis-Golgi Network Centrosome Cytosol Microtubule HOPS Complex Centriolar Satellite FHF Complex
	Molecular Function	Actin Binding Protein Binding Actin Filament Binding	Protein Binding Microtubule Binding Dynactin Binding Identical Protein Binding Dynein Light Chain Binding Dynein Intermediate Chain Binding Dynein Light Intermediate Chain Binding
	Biological Process	Intracellular Protein Transport Vacuole Organization Endosome To Lysosome Transport Endosomal Transport Regulation Of Vacuole Fusion, Non-autophagic Regulation Of SNARE Complex Assembly Autophagosome Maturation	Endosome Organization Lysosome Organization Endosome To Lysosome Transport Protein Transport Interkinetic Nuclear Migration Cytoskeleton-dependent Intracellular Transport Cytoplasmic Microtubule Organization Microtubule Anchoring At Centrosome Early Endosome To Late Endosome Transport Negative Regulation Of Neurogenesis Golgi Localization Protein Localization To Centrosome Neuronal Stem Cell Population Maintenance
Pathways
Drugs
Diseases
GWAS		Metabolite levels ( 23823483)	Zinc levels ( 26025379)
Interacting Genes		14 interacting genes: AKTIP FBXO7 HOOK1 HOOK2 HOOK3 MON1B RAB7A RILP STX1A STX7 UVRAG VPS11 VPS18 VPS33A	6 interacting genes: AKTIP HOOK1 HOOK2 MAPT VPS16 VPS41
Entrez ID		64601	84376
HPRD ID		12259	09699
Ensembl ID		ENSG00000215305	ENSG00000168172
Uniprot IDs		Q9H269	Q86VS8
PDB IDs		4BX9	5J8E 6B9H
Enriched GO Terms of Interacting Partners?
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