ATXN7 and NELL2

Number of citations of the paper that reports this interaction (PubMedID 21078624)
23

Data Source:
BioGRID (two hybrid)

		ATXN7	NELL2
Description		ataxin 7	neural EGFL like 2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytosol Microtubule Cytoskeleton Nuclear Matrix	Extracellular Region Cell Cytoplasm
	Molecular Function	Protein Binding	Protein Kinase C Binding Calcium Ion Binding Protein Binding Heparin Binding
	Biological Process	Microtubule Cytoskeleton Organization Nucleus Organization Negative Regulation Of Microtubule Depolymerization Visual Perception Histone Deubiquitination Protein Deubiquitination	Neuron Cellular Homeostasis
Pathways		HATs acetylate histones Ub-specific processing proteases	Regulation of commissural axon pathfinding by SLIT and ROBO
Drugs
Diseases		Spinocerebellar ataxia (SCA); Machado-Joseph disease (SCA3)
GWAS		anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Diastolic blood pressure ( 30224653) Estimated glomerular filtration rate ( 31152163) Schizophrenia ( 28991256 25056061 29483656) Type 2 diabetes ( 30054458)	Inflammatory bowel disease ( 27569725) Waist circumference ( 28552196)
Interacting Genes		60 interacting genes: ACTN1 ACTN2 ACTN4 ADAM33 AGRN CARD10 CEP70 CEP72 COG6 CRIM1 CRX EFEMP1 EFEMP2 FBN1 FN1 GOLGA2 GOLGA3 GPRASP1 GRN IMPDH2 ITPRID2 JAG2 KALRN KAT2A LAMB1 LAMB2 LRSAM1 LTBP4 MATN2 MEGF6 MPRIP NELL1 NELL2 NOC2L NUP62 PICK1 PNMA1 PPP1R12C PSMC1 RABEP1 RAD23A RNF31 SIAH1 SNX1 SPRY1 SUMO1 SUMO2 TAF10 THY1 TP53BP2 TRAF2 TRIM23 TRIM27 TRIM54 TRRAP TXNDC11 UBQLN2 USP22 VCP VWF	6 interacting genes: ATN1 ATXN7 BRD4 CACNA1A GFI1B PRKAR1A
Entrez ID		6314	4753
HPRD ID		06365	11891
Ensembl ID		ENSG00000163635	ENSG00000184613
Uniprot IDs		O15265 Q9UPD8	A0A024R0X1 B7Z625 Q99435
PDB IDs		2KKR
Enriched GO Terms of Interacting Partners?
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