RALA and REPS1

Number of citations of the paper that reports this interaction (PubMedID 7623849)
91

Data Source:
HPRD (two hybrid, in vitro)

		RALA	REPS1
Description		RAS like proto-oncogene A	RALBP1 associated Eps domain containing 1
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Focal Adhesion Cell Surface Endocytic Vesicle Cytoplasmic Vesicle Membrane Cleavage Furrow Extracellular Exosome Flemming Body	Cytosol Plasma Membrane Clathrin-coated Pit
	Molecular Function	GTPase Activity Protein Binding GTP Binding Myosin Binding GDP Binding Ubiquitin Protein Ligase Binding Edg-2 Lysophosphatidic Acid Receptor Binding ATPase Binding	Calcium Ion Binding Protein Binding SH3 Domain Binding
	Biological Process	Neural Tube Closure Exocytosis Chemotaxis Cell Cycle Signal Transduction Ras Protein Signal Transduction Regulation Of Exocytosis Actin Cytoskeleton Reorganization Interleukin-12-mediated Signaling Pathway Cell Division Positive Regulation Of Filopodium Assembly Membrane Raft Localization Membrane Organization	Receptor-mediated Endocytosis Membrane Organization
Pathways		Translocation of SLC2A4 (GLUT4) to the plasma membrane p38MAPK events Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation	Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis
Drugs		Guanosine-5'-Diphosphate
Diseases
GWAS			Response to serotonin reuptake inhibitors in major depressive disorder ( 25897834)
Interacting Genes		36 interacting genes: ACTB AKAP10 ARF1 C1QC CALM1 CNKSR2 CTCF EXOC1 EXOC2 EXOC3 EXOC4 EXOC5 EXOC6B EXOC7 EXOC8 FLNA GCK GLS2 HOXA2 HSPB1 INHBA LSM2 PIH1D2 PLCD1 PLD1 PPP2R1B RAB34 RAB8B RALBP1 RALGPS1 RASSF5 REPS1 RGL2 RGL4 SMAD4 YBX3	13 interacting genes: ATF4 CRK GRB2 HSF1 ITSN2 PIN1 RAB11FIP2 RALA RALB RALBP1 REPS2 TRAPPC2L WWC2
Entrez ID		5898	85021
HPRD ID		01549	09687
Ensembl ID		ENSG00000006451	ENSG00000135597
Uniprot IDs		P11233	B2R7D3 Q96D71
PDB IDs		1UAD 1ZC3 1ZC4 2A78 2A9K 2BOV
Enriched GO Terms of Interacting Partners?
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