RALA and EXOC5

Number of citations of the paper that reports this interaction (PubMedID 11406615)
51

Data Source:
HPRD (in vitro)

		RALA	EXOC5
Description		RAS like proto-oncogene A	exocyst complex component 5
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Focal Adhesion Cell Surface Endocytic Vesicle Cytoplasmic Vesicle Membrane Cleavage Furrow Extracellular Exosome Flemming Body	Exocyst Cytoplasm Cytosol Midbody
	Molecular Function	GTPase Activity Protein Binding GTP Binding Myosin Binding GDP Binding Ubiquitin Protein Ligase Binding Edg-2 Lysophosphatidic Acid Receptor Binding ATPase Binding	Protein Binding Ral GTPase Binding Protein N-terminus Binding
	Biological Process	Neural Tube Closure Exocytosis Chemotaxis Cell Cycle Signal Transduction Ras Protein Signal Transduction Regulation Of Exocytosis Actin Cytoskeleton Reorganization Interleukin-12-mediated Signaling Pathway Cell Division Positive Regulation Of Filopodium Assembly Membrane Raft Localization Membrane Organization	Establishment Of Planar Polarity Exocytosis Post-Golgi Vesicle-mediated Transport Golgi To Plasma Membrane Transport Protein Transport Vesicle Docking Protein Localization To Plasma Membrane Epithelial Cell Apoptotic Process Non-motile Cilium Assembly
Pathways		Translocation of SLC2A4 (GLUT4) to the plasma membrane p38MAPK events Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation	Translocation of SLC2A4 (GLUT4) to the plasma membrane Insulin processing VxPx cargo-targeting to cilium
Drugs		Guanosine-5'-Diphosphate
Diseases
GWAS			Alcohol consumption ( 23743675) Chronotype ( 30696823) Response to ranibizumab in age-related macular degeneration (exudative) ( 30054556)
Interacting Genes		36 interacting genes: ACTB AKAP10 ARF1 C1QC CALM1 CNKSR2 CTCF EXOC1 EXOC2 EXOC3 EXOC4 EXOC5 EXOC6B EXOC7 EXOC8 FLNA GCK GLS2 HOXA2 HSPB1 INHBA LSM2 PIH1D2 PLCD1 PLD1 PPP2R1B RAB34 RAB8B RALBP1 RALGPS1 RASSF5 REPS1 RGL2 RGL4 SMAD4 YBX3	34 interacting genes: ACTR3B ADCK1 ARF6 BARD1 BRMS1L CCDC102B CDH2 DEUP1 DNAAF4 EDRF1 ENO2 FRMD6 GNB1 HDDC3 HGS ICA1 KXD1 MAGEA6 OAS1 PRKCG PSTPIP1 PTK6 PYCARD RAB14 RAB4A RAB4B RALA SOX10 SPACA9 TBX21 TNPO2 TTC23L TXLNB TXNL4A
Entrez ID		5898	10640
HPRD ID		01549	07258
Ensembl ID		ENSG00000006451	ENSG00000070367
Uniprot IDs		P11233	O00471
PDB IDs		1UAD 1ZC3 1ZC4 2A78 2A9K 2BOV
Enriched GO Terms of Interacting Partners?
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