REPS1 and RALBP1

Number of citations of the paper that reports this interaction (PubMedID 28514442)
199

Data Source:
BioGRID (biochemical, affinity chromatography technology, pull down)
HPRD (two hybrid, in vivo, in vitro)

		REPS1	RALBP1
Description		RALBP1 associated Eps domain containing 1	ralA binding protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Plasma Membrane Clathrin-coated Pit	Cytosol Membrane
	Molecular Function	Calcium Ion Binding Protein Binding SH3 Domain Binding	GTPase Activator Activity Protein Binding Ral GTPase Binding Transmembrane Transporter Activity ATPase Activity, Coupled To Transmembrane Movement Of Substances Xenobiotic Transmembrane Transporter Activity Rac GTPase Binding
	Biological Process	Receptor-mediated Endocytosis Membrane Organization	Endocytosis Chemotaxis Small GTPase Mediated Signal Transduction Regulation Of GTPase Activity Positive Regulation Of GTPase Activity Regulation Of Small GTPase Mediated Signal Transduction Transmembrane Transport Doxorubicin Transport Drug Transmembrane Export
Pathways		Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis	Rho GTPase cycle
Drugs
Diseases
GWAS		Response to serotonin reuptake inhibitors in major depressive disorder ( 25897834)	LDL cholesterol ( 30275531)
Interacting Genes		13 interacting genes: ATF4 CRK GRB2 HSF1 ITSN2 PIN1 RAB11FIP2 RALA RALB RALBP1 REPS2 TRAPPC2L WWC2	30 interacting genes: AMOTL2 AP2M1 C1orf216 CASP8 CCNB1 CEP57 FADD GSE1 HOOK2 HSF1 IKBKG PLCG2 PPL PRKACA PRKCA RAC1 RALA RALB REPS1 REPS2 RHOU SMARCE1 SYNJ2BP TBRG1 TFPT TNIP1 TRAF2 TSFM ZBTB38 ZNF707
Entrez ID		85021	10928
HPRD ID		09687	09013
Ensembl ID		ENSG00000135597	ENSG00000017797
Uniprot IDs		B2R7D3 Q96D71	Q15311
PDB IDs			2KWH 2KWI 2MBG
Enriched GO Terms of Interacting Partners?
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