EPS15L1 and AGFG2

Number of citations of the paper that reports this interaction (PubMedID 9303539)
115

Data Source:
BioGRID (genetic interference)
HPRD (in vitro)

		EPS15L1	AGFG2
Description		epidermal growth factor receptor pathway substrate 15 like 1	ArfGAP with FG repeats 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol Plasma Membrane Membrane Clathrin Coat Of Coated Pit	Membrane
	Molecular Function	Calcium Ion Binding Protein Binding Cadherin Binding	Molecular_function GTPase Activator Activity Metal Ion Binding
	Biological Process	Endocytosis Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Membrane Organization	Biological_process Positive Regulation Of GTPase Activity
Pathways		EGFR downregulation Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis
Drugs
Diseases
GWAS		Eosinophil percentage of granulocytes ( 27863252) Lymphocyte counts ( 29403010 27863252) Lymphocyte percentage of white cells ( 27863252) Monocyte percentage of white cells ( 27863252) Multiple sclerosis ( 31604244 22190364 24076602) Neutrophil percentage of granulocytes ( 27863252) Neutrophil percentage of white cells ( 27863252) White blood cell count ( 27863252 21738480) White matter integrity ( 23218918)	Hematocrit ( 27863252)
Interacting Genes		12 interacting genes: AGFG1 AGFG2 EPN1 FCHO1 FCHO2 GNG5 ITSN1 ITSN2 SGIP1 STON2 TRAPPC2B UBC	4 interacting genes: APP EPS15 EPS15L1 ITSN1
Entrez ID		58513	3268
HPRD ID		09445	04932
Ensembl ID		ENSG00000127527	ENSG00000106351
Uniprot IDs		A0A024R7G6 Q9UBC2	A4D2D6 O95081
PDB IDs
Enriched GO Terms of Interacting Partners?
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