AGFG2 and EPS15L1

Number of citations of the paper that reports this interaction (PubMedID 9303539)
115

Data Source:
BioGRID (genetic interference)
HPRD (in vitro)

		AGFG2	EPS15L1
Description		ArfGAP with FG repeats 2	epidermal growth factor receptor pathway substrate 15 like 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Membrane	Nucleus Cytosol Plasma Membrane Membrane Clathrin Coat Of Coated Pit
	Molecular Function	Molecular_function GTPase Activator Activity Metal Ion Binding	Calcium Ion Binding Protein Binding Cadherin Binding
	Biological Process	Biological_process Positive Regulation Of GTPase Activity	Endocytosis Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Membrane Organization
Pathways			EGFR downregulation Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis
Drugs
Diseases
GWAS		Hematocrit ( 27863252)	Eosinophil percentage of granulocytes ( 27863252) Lymphocyte counts ( 29403010 27863252) Lymphocyte percentage of white cells ( 27863252) Monocyte percentage of white cells ( 27863252) Multiple sclerosis ( 31604244 22190364 24076602) Neutrophil percentage of granulocytes ( 27863252) Neutrophil percentage of white cells ( 27863252) White blood cell count ( 27863252 21738480) White matter integrity ( 23218918)
Interacting Genes		4 interacting genes: APP EPS15 EPS15L1 ITSN1	12 interacting genes: AGFG1 AGFG2 EPN1 FCHO1 FCHO2 GNG5 ITSN1 ITSN2 SGIP1 STON2 TRAPPC2B UBC
Entrez ID		3268	58513
HPRD ID		04932	09445
Ensembl ID		ENSG00000106351	ENSG00000127527
Uniprot IDs		A4D2D6 O95081	A0A024R7G6 Q9UBC2
PDB IDs
Enriched GO Terms of Interacting Partners?
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