EPS15L1 and AGFG1

Number of citations of the paper that reports this interaction (PubMedID 10613896)
21

Data Source:
HPRD (in vivo, two hybrid)

		EPS15L1	AGFG1
Description		epidermal growth factor receptor pathway substrate 15 like 1	ArfGAP with FG repeats 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol Plasma Membrane Membrane Clathrin Coat Of Coated Pit	Nuclear Pore Cytosol Cytoplasmic Vesicle Cell Projection Neuronal Cell Body Intracellular Membrane-bounded Organelle
	Molecular Function	Calcium Ion Binding Protein Binding Cadherin Binding	DNA Binding RNA Binding GTPase Activator Activity Protein Binding Metal Ion Binding
	Biological Process	Endocytosis Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Membrane Organization	Acrosome Assembly MRNA Export From Nucleus Multicellular Organism Development Spermatid Nucleus Differentiation Positive Regulation Of GTPase Activity Intermediate Filament Organization Membrane Organization
Pathways		EGFR downregulation Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis	Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis
Drugs
Diseases
GWAS		Eosinophil percentage of granulocytes ( 27863252) Lymphocyte counts ( 29403010 27863252) Lymphocyte percentage of white cells ( 27863252) Monocyte percentage of white cells ( 27863252) Multiple sclerosis ( 31604244 22190364 24076602) Neutrophil percentage of granulocytes ( 27863252) Neutrophil percentage of white cells ( 27863252) White blood cell count ( 27863252 21738480) White matter integrity ( 23218918)	Airway hyperresponsiveness ( 23984888) Mild influenza (H1N1) infection ( 26379185)
Interacting Genes		12 interacting genes: AGFG1 AGFG2 EPN1 FCHO1 FCHO2 GNG5 ITSN1 ITSN2 SGIP1 STON2 TRAPPC2B UBC	13 interacting genes: APC APP DNAJC5 EPS15 EPS15L1 ITSN1 MFHAS1 NYAP2 PKIA POLE2 RNF216 VAMP7 XPO1
Entrez ID		58513	3267
HPRD ID		09445	02918
Ensembl ID		ENSG00000127527	ENSG00000173744
Uniprot IDs		A0A024R7G6 Q9UBC2	A0A0S2Z3Y3 A0A0S2Z3Z1 A0A0S2Z444 A0A0S2Z462 P52594
PDB IDs			2D9L 2OLM 2VX8
Enriched GO Terms of Interacting Partners?
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