CAMK1D and TNFSF13

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		CAMK1D	TNFSF13
Description		calcium/calmodulin dependent protein kinase ID	TNF superfamily member 13
Image
GO Annotations	Cellular Component	Intracellular Nucleus Cytoplasm	Extracellular Region Nucleoplasm Cytoplasm Cytosol Membrane Extracellular Exosome
	Molecular Function	Protein Serine/threonine Kinase Activity Calmodulin-dependent Protein Kinase Activity Calmodulin Binding ATP Binding	Signaling Receptor Binding Cytokine Activity Tumor Necrosis Factor Receptor Binding
	Biological Process	Protein Phosphorylation Inflammatory Response Positive Regulation Of Neuron Projection Development Positive Regulation Of CREB Transcription Factor Activity Positive Regulation Of Apoptotic Process Negative Regulation Of Apoptotic Process Positive Regulation Of Phagocytosis Regulation Of Dendrite Development Positive Regulation Of Respiratory Burst Regulation Of Granulocyte Chemotaxis Positive Regulation Of Neutrophil Chemotaxis	Immune Response Signal Transduction Positive Regulation Of Cell Proliferation Tumor Necrosis Factor-mediated Signaling Pathway Regulation Of MRNA Stability Positive Regulation Of Isotype Switching To IgA Isotypes
Pathways			HuR (ELAVL1) binds and stabilizes mRNA TNFs bind their physiological receptors
Drugs		N-(5-METHYL-1H-PYRAZOL-3-YL)-2-PHENYLQUINAZOLIN-4-AMINE
Diseases
GWAS		Anorexia nervosa ( 23568457) Bipolar disorder ( 31043756) Body mass index ( 28892062) Borderline personality disorder ( 28632202) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Coronary artery aneurysm in Kawasaki disease ( 27171184) Eating disorders ( 23568457) Headache ( 29397368) Height ( 31562340) Household income (MTAG) ( 31844048) Obesity-related traits ( 23251661) QT interval (drug interaction) ( 23459443) Response to cyclophosphamide in systemic lupus erythematosus with lupus nephritis ( 26980576) Tea consumption ( 31046077) Type 2 diabetes ( 22885922 18372903 26961502 20862305 29358691 30297969 26818947 30718926)	Albumin-globulin ratio ( 29403010) Bitter alcoholic beverage consumption ( 31046077) Chin dimples ( 27182965) Composite immunoglobulin trait (IgA x IgG x IgM) ( 28628107) Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) IgA levels ( 22864923 28628107) IgA nephropathy ( 26028593 25305756 22197929) IgM levels ( 23118916) Myopia ( 27182965) Non-albumin protein levels ( 22558069 29403010) Serum total protein level ( 29403010) Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858)
Interacting Genes		12 interacting genes: APP ASAH1 BNIP3L CAMKK1 CDC25A CUL3 GMFG LRRK2 NEDD4 NEDD4L POT1 TNFSF13	12 interacting genes: CAMK1D FAS FURIN KRAS PIK3CA SDC2 TNFRSF11B TNFRSF13B TNFRSF14 TNFRSF17 TNFRSF1A TNFSF13B
Entrez ID		57118	8741
HPRD ID		06409	05128
Ensembl ID		ENSG00000183049	ENSG00000161955
Uniprot IDs		Q5SQQ7 Q8IU85	B3KR02 O75888 Q2QBA2
PDB IDs		2JC6 6T28 6T29	4ZCH
Enriched GO Terms of Interacting Partners?
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