TNFSF13 and TNFSF13B

Number of citations of the paper that reports this interaction (PubMedID 12370363)
48

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology)
HPRD (in vitro)

		TNFSF13	TNFSF13B
Description		TNF superfamily member 13	TNF superfamily member 13b
Image
GO Annotations	Cellular Component	Extracellular Region Nucleoplasm Cytoplasm Cytosol Membrane Extracellular Exosome	Extracellular Region Extracellular Space Cytoplasm Plasma Membrane Integral Component Of Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	Signaling Receptor Binding Cytokine Activity Tumor Necrosis Factor Receptor Binding	Signaling Receptor Binding Cytokine Activity Tumor Necrosis Factor Receptor Binding Protein Binding
	Biological Process	Immune Response Signal Transduction Positive Regulation Of Cell Proliferation Tumor Necrosis Factor-mediated Signaling Pathway Regulation Of MRNA Stability Positive Regulation Of Isotype Switching To IgA Isotypes	B Cell Homeostasis Positive Regulation Of Germinal Center Formation Immune Response Signal Transduction Positive Regulation Of B Cell Proliferation T Cell Costimulation B Cell Costimulation Tumor Necrosis Factor-mediated Signaling Pathway Positive Regulation Of T Cell Proliferation Immunoglobulin Secretion
Pathways		HuR (ELAVL1) binds and stabilizes mRNA TNFs bind their physiological receptors	TNFR2 non-canonical NF-kB pathway TNFs bind their physiological receptors TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway
Drugs			1,4-Diethylene Dioxide Citric Acid Belimumab
Diseases
GWAS		Albumin-globulin ratio ( 29403010) Bitter alcoholic beverage consumption ( 31046077) Chin dimples ( 27182965) Composite immunoglobulin trait (IgA x IgG x IgM) ( 28628107) Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) IgA levels ( 22864923 28628107) IgA nephropathy ( 26028593 25305756 22197929) IgM levels ( 23118916) Myopia ( 27182965) Non-albumin protein levels ( 22558069 29403010) Serum total protein level ( 29403010) Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858)	Blood protein levels ( 30072576) IgG levels ( 28628107) Metabolite levels ( 23823483) Myeloid white cell count ( 27863252) Non-albumin protein levels ( 29403010) Platelet count ( 27863252) Platelet distribution width ( 27863252) Plateletcrit ( 27863252) Tonsillectomy ( 27182965 28928442) Venous thromboembolism adjusted for sickle cell variant rs77121243-T ( 28203683) White blood cell count ( 27863252)
Interacting Genes		12 interacting genes: CAMK1D FAS FURIN KRAS PIK3CA SDC2 TNFRSF11B TNFRSF13B TNFRSF14 TNFRSF17 TNFRSF1A TNFSF13B	5 interacting genes: APP TNFRSF13B TNFRSF13C TNFRSF17 TNFSF13
Entrez ID		8741	10673
HPRD ID		05128	04914
Ensembl ID		ENSG00000161955	ENSG00000102524
Uniprot IDs		B3KR02 O75888 Q2QBA2	A0A0U5J7Q1 Q9Y275
PDB IDs		4ZCH	1JH5 1KD7 1KXG 1OQD 1OQE 1OSG 3V56 4V46 4ZCH 5Y9J 6FXN
Enriched GO Terms of Interacting Partners?
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