RBM23 and POLA2

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		RBM23	POLA2
Description		RNA binding motif protein 23	DNA polymerase alpha 2, accessory subunit
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GO Annotations	Cellular Component	Nucleus Membrane Ribonucleoprotein Complex	Nucleoplasm Alpha DNA Polymerase:primase Complex Cytosol
	Molecular Function	RNA Binding Protein Binding	Molecular_function DNA Binding DNA-directed DNA Polymerase Activity
	Biological Process	MRNA Processing Regulation Of RNA Metabolic Process	G1/S Transition Of Mitotic Cell Cycle DNA Replication DNA Replication Initiation Telomere Maintenance Via Semi-conservative Replication DNA Biosynthetic Process
Pathways			Inhibition of replication initiation of damaged DNA by RB1/E2F1 Polymerase switching on the C-strand of the telomere Telomere C-strand synthesis initiation DNA replication initiation Activation of the pre-replicative complex Polymerase switching Removal of the Flap Intermediate Processive synthesis on the lagging strand
Drugs			Dacarbazine
Diseases
GWAS		Cognitive ability (MTAG) ( 29186694) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Cortical amyloid beta load ( 29860282) Vertical cup-disc ratio (multi-trait analysis) ( 31959993)	Acne (severe) ( 24927181)
Interacting Genes		25 interacting genes: BHLHE40 CDK6 CEP126 CHERP ESR1 FAM9B FBXO7 GTF3C1 MAGEA11 MAGED1 MED31 PGR POLA2 PRMT5 PTN QKI RBFOX2 RBM25 RBM39 RBM4 RPA1 SRPK1 SRPK2 TRIM27 TUBA4A	41 interacting genes: AGO2 AKTIP APP ARL2 ASCC2 ATL3 ATP5F1C CATSPERZ CPE CRELD1 DCP2 DDX24 DHX34 EIF6 EZH2 FAM219A FGFR3 FRZB HDAC6 HELB HGH1 IGFBP3 KCNE3 KDM2A KLF6 LRPAP1 MFHAS1 NR4A1 PARP1 POLA1 PRIM2 PRPF38A RBM23 SAC3D1 SETDB1 SNU13 STK40 TMEM216 ULK2 XPNPEP1 ZNRD2
Entrez ID		55147	23649
HPRD ID		15227	10160
Ensembl ID		ENSG00000100461	ENSG00000014138
Uniprot IDs		A0A0S2Z5D9 A0A0S2Z5I1 A0A0S2Z5J3 B7Z8M4 G3XAP0 Q86U06	Q14181
PDB IDs		2CQ4 2DNZ	2KEB 4E2I 4Y97 5EXR
Enriched GO Terms of Interacting Partners?
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